21062-19-1

Basic information

• Product Name: 1,4-benzenediacetyl dichloride
• Synonyms: 1,4-benzenediacetyl dichloride
• CAS NO: 21062-19-1
• Molecular Weight: 231.078
• Mol File: 21062-19-1.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 1,4-benzenediacetyl dichloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-benzenediacetyl dichloride(21062-19-1)
• EPA Substance Registry System: 1,4-benzenediacetyl dichloride(21062-19-1)

Safety Data

• Hazardous Substances Data: 21062-19-1(Hazardous Substances Data)

Upstream product

• 622-75-3 1,4-phenylenediacetonitrile 
• 623-25-6 p-Xylylene dichloride 
• 7325-46-4 1,4-phenylenediacetic acid 

Downstream Products

• 102702-54-5 p-phenylenedi-acetic acid bis-(2-diethylamino-ethyl ester) 
• 115754-28-4 {2-[4-(2-Oxo-2-ureido-ethyl)-phenyl]-acetyl}-urea 
• 115754-29-5 1-Methyl-3-(2-{4-[2-(3-methyl-ureido)-2-oxo-ethyl]-phenyl}-acetyl)-urea 
• 62667-40-7 1.4-Benzoldiperessigsaeure-tert.-butylester 
• 622407-53-8 [4-(3-methyl-oxetan-3-ylmethoxycarbonylmethyl)-phenyl]-acetic acid 3-methyl-oxetan-3-ylmethyl ester 
• 1351472-50-8 N,N’-bis(3-(pyrrolidin-1-yl)propyl)-1,4-bis(2-aminoeth-1-yl)benzene 
• 1351472-53-1 N,N’-bis(2-(pyrrolidin-1-yl)ethyl)-1,4-bis(2-aminoeth-1-yl)benzene 
• 1351472-55-3 N,N’-bis(3-(2-pipecolin-1-yl)propyl)-1,4-bis(2-aminoeth-1-yl)benzene 
• 1351472-58-6 N,N’-bis(3-(piperidin-1-yl)propyl)-1,4-bis(2-aminoeth-1-yl)benzene 
• 1351472-63-3 N,N’-bis(2-(piperidin-1-yl)ethyl)-1,4-bis(2-aminoeth-1-yl)benzene 

Relevant articles and documents

Recognition of insoluble tartaric acid in chloroform

Simple receptors for the recognition and solubilisation of insoluble tartaric acid in chloroform were designed and synthesised for the first time. Receptors 2 and 3 were successful in solubilising tartaric acid into chloroform forming a 1:1 complex, and w

The Cooperative Effect of Both Molecular and Supramolecular Chirality on Cell Adhesion

Although helical nanofibrous structures have great influence on cell adhesion, the role played by chiral molecules in these structures on cells behavior has usually been ignored. The chirality of helical nanofibers is inverted by the odd–even effect of methylene units from homochiral l-phenylalanine derivative during assembly. An increase in cell adhesion on left-handed nanofibers and weak influence of cell behaviors on right-handed nanofibers are observed, even though both were derived from l-phenylalanine derivatives. Weak and negative influences on cell behavior was also observed for left- and right-handed nanofibers derived from d-phenylalanine, respectively. The effect on cell adhesion of single chiral molecules and helical nanofibers may be mutually offset.

Novel bivalent securinine mimetics as topoisomerase I inhibitors

A series of novel bivalent securinine mimetics incorporating different linkers between C-15 and C-15′ were synthesized and their topoisomerase I (Topo I) inhibitory activities evaluated. It was thus revealed that mimetic R2 incorporating a rigid m-substituted benzene linker exhibits Topo I inhibitory activity three times that of parent securinine. Comprehensive structure-activity relationship analyses in combination with docking studies were used to rationalize the potent activity of these bivalent mimetics. Mechanistic studies served to confirm the deductions arising from docking studies that the active bivalent mimetics not only inhibited complexation between Topo I and DNA but also stabilized the Topo I-DNA complex itself.