210627-73-9

Upstream product

• 10311-08-7 dimethyl(phenyl)phosphine oxide 
• 345-92-6 4,4'-Difluorobenzophenone 

Downstream Products

• 6175-14-0 1,1-bis-(4-fluorophenyl)ethene 
• 210627-89-7 2,2,6,6-Tetrakis-(4-fluoro-phenyl)-4-phenyl-1,5-dioxa-4λ⁵-phospha-spiro[3.3]heptane 

Relevant academic research and scientific papers

Synthesis and double olefin extrusion of 2,2,6,6-tetraaryl-1,5-dioxa-4λ5-phosphaspiro[3.3]heptanes

The title compounds were synthesized by cyclization and dehydration of the corresponding bis(β-hydroxyalkyl)phosphine oxides with Appel's reagent. Since these compounds were very moisture sensitive to hydrolyze to the starting bis(β-hydroxyalkyl)phosphine oxides except for tetrakis(4-nitrophenyl) derivative, their in-situ generation and thermolysis were carried out to give two molar equivalents of the corresponding olefins in good yield in sharp contrast to tetrakis(trifluoromethyl) derivative.