21063-30-9

Basic information

• Product Name: 17-(hydroxyimino)androst-5-en-3-yl acetate
• Synonyms: (3β,17E)-17-(hydroxyimino)androst-5-en-3-yl acetate
• CAS NO: 21063-30-9
• Molecular Formula: C₂₁H₃₁NO₃
• Molecular Weight: 345.4757
• Mol File: 21063-30-9.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 467.681°C at 760 mmHg
• Flash Point: 236.645°C
• Density: 1.278g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.627
• CAS DataBase Reference: 17-(hydroxyimino)androst-5-en-3-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 17-(hydroxyimino)androst-5-en-3-yl acetate(21063-30-9)
• EPA Substance Registry System: 17-(hydroxyimino)androst-5-en-3-yl acetate(21063-30-9)

Safety Data

• Hazardous Substances Data: 21063-30-9(Hazardous Substances Data)

Usage

Chemical class

Belongs to the class of androgens, which are hormones that promote the development of male sexual characteristics.

Derivative

A derivative of testosterone, a naturally occurring androgen.

Use

Often used in the production of anabolic steroids.

Receptor binding

Has the ability to bind to androgen receptors in the body.

Muscle growth

Leads to increased muscle growth and strength.

Red blood cell production

Potential to increase the production of red blood cells.

Endurance and athletic performance

Improved endurance and athletic performance due to increased red blood cell production.

Negative health effects

Can lead to liver damage, cardiovascular problems, and hormonal imbalances.

Regulation and restriction

Use is highly regulated and restricted in many countries due to potential health risks.

Upstream product

• 53-43-0 dehydroepiandrosterone 
• 1093959-59-1 3β-hydroxypregn-5-en-20-one-3-acetate 
• 512-04-9 diosgenin 
• 979-02-2 16-dehydropregnenolone acetate 
• 23549-24-8 3β-acetoxy-20-hydroxyiminopregna-5,16-diene 
• 1232-19-5 17-hydroxyiminoandrost-5-en-3β-ol 
• 108-24-7 acetic anhydride 
• 853-23-6 prasterone acetate 

Downstream Products

• 1126086-35-8 17-oximino-5-androsten-3β-yl 4-nitrobenzoate 
• 1126086-38-1 17-oximino-5-androsten-3β-yl 4-aminobenzoate 
• 1126086-39-2 17-oximino-5-androsten-3β-yl 4-hydroxybenzoate 
• 1252553-11-9 17-oximino-5-androsten-3β-yl 4-methoxybenzoate 
• 1126086-34-7 17-oximino-5-androsten-3β-yl 4-chlorobenzoate 
• 1126086-37-0 17-oximino-5-androsten-3β-yl 4-methylbenzoate 
• 1600-81-3 (10aR,12aS)-10a,12a-dimethyl-4,4a,4b,5,6,9,10,10a,10b,11,12,12a-dodecahydronaphtho[2,1-f]quinoline-2,8(1H,3H)-dione 
• 1393748-68-9 17a-aza-17a-benzyl-17-oxo-17a-homoandrosta-3,5-dien-3-oic acid 
• 1393748-64-5 17a-aza-17a-benzoyl-3-cyano-17a-homoandrosta-3,5-dien-17-one 
• 1393748-59-8 17a-aza-17a-benzyl-3-cyano-17a-homoandrosta-3,5-dien-17-one 
• 7680-15-1 3β-hydroxy-13α-amino-13,17-seco-5-androsten-17-oic-13,17-lactam 

Relevant articles and documents

Synthesis, Crystal Structure, and Insecticidal Activity of Steroidal N-Piperidone

A series of steroidal piperidone derivatives were synthesized, and their agricultural activities were evaluated against Myzus persicae, Aphis citricola, Brevicoryne brassicae Linn., and Bemisia tabaci (Gennadius). Most of the tested compounds exhibited potent insecticidal activity against these four pests. Compound I-9 displayed the highest activity against M. persicae, A. citricola, and Brevicoryne brassicae, with LC50 values of 11.3, 10.4, and 8.68 μg/mL, respectively. The mode of action test indicated that these derivatives had superior contact and systemic insecticidal activity against M. persicae. In addition, we initially explored whether the foregut and midgut might be the action sites of the target derivatives against M. persicae. Furthermore, a field trial showed that the control of compound I-9 was similar to that of acetamiprid against M. persicae, at a dose of 50 μg/mL; the control rates were 97.8 and 99.2% after 14 and 21 days, respectively. The structure-activity relationship of these analogues provided some important insights for the discovery and development of new insecticides to solve the current pesticide resistance crisis.

Steroid piperidone derivatives and synthesis methods and applications thereof

The present invention discloses a steroidal piperidone derivative and its synthesis method and application, steroid piperidone derivative having a chemical structure expressed by formula (1) or formula (2), wherein R is an alkyl, phenyl or substituted phenyl and any one of the heterocyclic; Is the best method for the preparation of steroid piperidone derivatives of the present invention; the steroid piperidone derivatives provided by the present invention have been bioassayed to confirm that aphids, leaf mites, rice planthoppers and whiteflies and other sucking insects exhibit good toxicity and activity, can be applied to plant pest control.

Sensitized Aliphatic Fluorination Directed by Terpenoidal Enones: A "visible Light" Approach

In our continued effort to address the challenges of selective sp3 C-H fluorination on complex molecules, we report a sensitized aliphatic fluorination directed by terpenoidal enones using catalytic benzil and visible light (white LEDs). This sensitized approach is mild, simple to set up, and an economical alternative to our previous protocol based on direct excitation using UV light in a specialized apparatus. Additionally, the amenability of this protocol to photochemical flow conditions and preliminary evidence for electron-transfer processes are highlighted.