210685-04-4

Upstream product

• 165537-90-6 6-(4-Chlorophenylsulfonyl)amino-2-oxo-5,6,7,8-tetrahydro-2H-benzo[e]pyran 

Downstream Products

• 210685-05-5 3-Bromo-6-(4-chloro-benzenesulfonylamino)-2-trimethylsilanyl-5,6,7,8-tetrahydro-naphthalene-1-carboxylic acid ethyl ester 
• 165538-30-7 N-(7-Bromo-5-hydroxymethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-4-chloro-benzenesulfonamide 
• 165538-00-1 4-Chloro-N-(5-formyl-6,7-dimethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-benzenesulfonamide 
• 210535-32-3 N-(7-Bromo-5-formyl-6-propyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-4-chloro-benzenesulfonamide 
• 210535-34-5 N-(7-Bromo-5-formyl-6-pentyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-4-chloro-benzenesulfonamide 
• 165538-01-2 (E)-3-[6-(4-Chloro-benzenesulfonylamino)-2,3-dimethyl-5,6,7,8-tetrahydro-naphthalen-1-yl]-acrylic acid methyl ester 
• 165538-02-3 3-[6-(4-Chloro-benzenesulfonylamino)-2,3-dimethyl-5,6,7,8-tetrahydro-naphthalen-1-yl]-propionic acid methyl ester 
• 210535-38-9 4-Chloro-N-(5-formyl-6-methyl-7-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-benzenesulfonamide 
• 210535-40-3 4-Chloro-N-(5-formyl-6-propyl-7-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-benzenesulfonamide 
• 210535-44-7 4-Chloro-N-(5-formyl-6-phenyl-7-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-benzenesulfonamide 
• 210535-42-5 4-Chloro-N-(5-formyl-6-pentyl-7-pyridin-3-ylmethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-benzenesulfonamide 

Relevant academic research and scientific papers

Synthesis and biological evaluation of new tetrahydronaphthalene derivatives as thromboxane receptor antagonists

New polysubstituted tetrahydronaphthalene derivatives were prepared as thromboxane receptor (TP-receptor) antagonists. Within this series of compounds S 18886 has been identified as an orally active, highly potent antagonist with a very long duration of action in different species.

1,2,3,4-tetrahydronaphthalene compounds

R1 and R2 form, with the carbon atoms to which they are attached, cyclopentane or cyclohexane, R3 represents hydroxyl, linear or branched (C1 -C6) alkoxy or unsubstituted or substituted amino,