Synthesis and biological evaluation of new tetrahydronaphthalene derivatives as thromboxane receptor antagonists

DOI: 10.1016/S0960-894X(98)00220-0

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1375 - 1380 (1998)

Update date:2022-08-05

Topics:

Authors:

Cimetiere, Bernard

Dubuffet, Thierry

Muller, Olivier

Descombes, Jean-Jacques

Simonet, Serge

Laubie, Michel

Verbeuren, Tony J.

Lavielle, Gilbert

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00220-0

New polysubstituted tetrahydronaphthalene derivatives were prepared as thromboxane receptor (TP-receptor) antagonists. Within this series of compounds S 18886 has been identified as an orally active, highly potent antagonist with a very long duration of action in different species.

Full text of DOI:10.1016/S0960-894X(98)00220-0

Products guided by the article

Product name:3-Bromo-6-(4-chlorophenylsulfonyl)amino-2-oxo-5,6,7,8-tetrahydro-2H-benzo[e]pyran

Cas No:210685-04-4

R&D Labs maybe for 210685-04-4

Jinan Jinguilin Chemical Co.,Ltd

Contact:+86-531-81188412

Address:3rd floor of Torch Building, Huanyuan Rd, City of Jinan
Chongqing KonAo Health Co.,Ltd

Contact:13687578375

Address:wuhan hubei china
JenKem Technology Co., Ltd.

Contact:86-10-62983737; +86-10-51287608

Address:4/F Building C, 2 Shangdi Xinxi Road
Wuhan Shangrisyn chemicals Technology Co.,Ltd(expird)

Contact:+86-027-84466317 __ +86-15387123698

Address:wuhan - china
Jiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd

Contact:+86-0517-87036900

Address:Chuzhou Chemical park, Huai'an, Jiangsu Province

Relevant to this article

Introduction of C-sulfonate groups into disaccharide derivatives

Doi:10.1080/00397919808004290
(1998)
Electron density manipulation in rhodium(I) phosphine complexes: Structure of acetylacetonatocarbonylferrocenyl- diphenylphosphinerhodium(I)

Doi:10.1016/S0277-5387(98)00049-7
(1998)
Nucleophilic ¹⁸F-fluorination of phosphorofluoridates and phosphonofluoridic acids via imidazole-activated precursors

Doi:10.1016/j.tetlet.2021.152917
(2021)
Synthesis of Unsymmetrical Δ^4,4'-Bi-4H-pyrans and -thiopyrans

Doi:10.1021/jo01300a039
(1980)
Stereoselective construction of the tetracyclic scalarane skeleton from carvone

Doi:10.1039/a900081j
(1999)
Novel molecular organotin oxides derived from alkylidene bridged ditin precursors: Syntheses and structures

Doi:10.1021/om980369l
(1998)

Article Doi