21069-05-6Relevant academic research and scientific papers
Syntheses for 2-Hydroxy-2H-1,4-benzothiazin-3(4H)-one Derivatives as Thio Analogues of Natural Hemiacetals
Sicker, Dieter,Hartenstein, Holger,Hazard, Roland,Tallec, Andre
, p. 809 - 812 (2007/10/02)
Reductive cyclizations of methyl 2-(2-nitrophenylthio)acetate 2 by means of electrochemistry or by catalytic hydrogenation have been used as key steps in the syntheses of hemiacetals 2-hydroxy-2H-1,4-benzothiazin-3(4H)-one 10 and its 4-hydroxy derivative 9 representing thio analogues of allelo chemicals found in Gramineae and Acanthaceae.In contrast to its natural counterpart 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one hydroxamic acid 9 did not undergo degradation by extrusion of formic acid.
REACTIONS OF 4-ACETOXY-2H-1,4-BENZTHIAZIN-3(4H)-ONE
Kugai, Norio,Hashimoto, Yuichi,Shudo, Koichi
, p. 277 - 280 (2007/10/02)
4-Acetoxy-2H-1,4-benzthiazin-3(4H)-one (5), a unique arylhydroxamic acid derivative, reacted with nucleophiles.The position 2 of compound 5 is the center of high reactivity, and even benzene reacted with 5 nucleophilically at the position.
The Electrochemical Synthesis of Cyclic Hydroxamic Acids Followed by Bamberger Rearrangement
Matschiner, H.,Tanneberg, H.,Maschmeier, C.-P.
, p. 924 - 926 (2007/10/02)
The electrochemical reduction of 2-(o-nitro-phenylthio)acetic acid 1a results in the expected cyclic hydroxamic acid 3a and a rearranged product 4a by consuming 4 electrons.The analogous reduction of 2-(o-nitro-phenoxy)acetic acid 1b leads only to a rearr
