2107-85-9

Basic information

• Product Name: 5,6-Dimethoxy-2-nitroso-2,3-dihydro-1H-inden-1-one
• Synonyms: 5,6-Dimethoxy-2-nitroso-2,3-dihydro-1H-inden-1-one
• CAS NO: 2107-85-9
• Molecular Formula: C₁₁H₁₁NO₄
• Molecular Weight: 221.20934
• Mol File: 2107-85-9.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5,6-Dimethoxy-2-nitroso-2,3-dihydro-1H-inden-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-Dimethoxy-2-nitroso-2,3-dihydro-1H-inden-1-one(2107-85-9)
• EPA Substance Registry System: 5,6-Dimethoxy-2-nitroso-2,3-dihydro-1H-inden-1-one(2107-85-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 2107-85-9(Hazardous Substances Data)

Usage

General Description

5,6-Dimethoxy-2-nitroso-2,3-dihydro-1H-inden-1-one is a chemical compound with the molecular formula C11H11NO5. It is a yellow powder with a nitroso group and two methoxy groups attached to a dihydroindene ring. 5,6-Dimethoxy-2-nitroso-2,3-dihydro-1H-inden-1-one has been studied for its potential use in organic synthesis and as a reagent in chemical reactions. It may also have applications in pharmaceutical research and development due to its unique structure and interesting chemical properties. Further research is needed to fully understand the potential uses and properties of 5,6-Dimethoxy-2-nitroso-2,3-dihydro-1H-inden-1-one.

Upstream product

• 2107-69-9 5,6-dimethoxy-1-indanone 
• 544-16-1 n-Butyl nitrite 
• 2107-70-2 3,4-methoxycinnamic acid 
• 51842-87-6 3-(3,4-dimethoxy-phenyl)-propionyl chloride 
• 110-46-3 isopentyl nitrite 
• 624-91-9 methyl nitrite 

Downstream Products

• 76254-26-7 2-(cyanomethyl)-4,5-dimethoxybenzoic acid 
• 83598-55-4 5,6-Dimethoxy-2-indanylamine 
• 24634-09-1 2-(cyanomethyl)-4,5-dimethoxybenzoyl chloride 
• 1616296-09-3 C₂₂H₂₄ClN₃O₃ 
• 1616295-10-3 3-cyclopropyl-6,7-dimethoxy-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-isoquinoline 
• 24623-42-5 1,3-dichloro-6,7-dimethoxyisoquinoline 
• 1352035-40-5 C₃₁H₂₈N₂O₂ 
• 1352035-48-3 C₂₅H₂₅N₃O₂ 
• 1352035-47-2 C₂₄H₁₈N₂O₂ 
• 1352035-46-1 C₂₄H₂₂N₄O₂ 
• 1352036-18-0 3-([1,1:3',1''-terphenyl]-5'-yl)-1-chloro-6,7-dimethoxyisoquinoline 
• 1352035-45-0 C₂₄H₂₂N₂O₂ 
• 1352035-44-9 C₂₆H₂₇N₂O₂⁽¹⁺⁾*I^(1-) 
• 1352036-21-5 3-([1,1'-biphenyl]-3-yl)-1-chloro-6,7-dimethoxy-2-methylisoquinolin-2-ium iodide 

Relevant articles and documents

Efficient diastereoselective synthesis of cis-2-amino-1-indanol derivatives and cis- and trans-1-amino-2-indanol via Pd-catalyzed hydrogenation

(±)-cis-2-amino-1-indanol was diastereoselectively synthesized from 1,2-indanedion-2-oxime in ethanol at 25 °C under 10% Pd/C-catalyzed hydrogenation conditions. Under the same hydrogenation condition, 1,2-indanedion-2-oxime and their derivatives having one and/or two electron-donating groups in aliphatic or aromatic part of indanyl ring were diastereoselectively reduced to racemic cis-2-amino-1-indanol derivatives. From 1,2-indanedion-1-oxime, (±)-trans-1-amino-2-indanol was obtained in ethanol at 25 °C over a 10% Pd/BaSO4 catalyst. In contrast, the 10% Pd/BaSO4-catalyzed hydrogenation reaction in ethanol at 45 °C afforded cis-1-hydroxyamino-2-indanol from 1,2-indanedion-1-oxime, followed by reduction to form (±)-cis-1-amino-2-indanol. The diastereoselectivity of β-aminoindanols was dependent on the Pd catalyst, reaction temperature, and pH of the reaction medium.

Cu-catalyzed coupling of indanone oxime acetates with thiols to 2,3-difunctionalized indenones

A Cu-catalyzed coupling reaction of indanone oxime acetates with thiols has been developed for the synthesis of 2,3-functionalized 1-indenones. This protocol has several features including easy mild reaction conditions, stabilized enamine products, good t

Preparation method of 2-aminoindan derivative

The invention discloses a preparation method of a 2-aminoindan derivative. The preparation method comprises the following steps: with a 1-indanone derivative as a starting raw material, carrying out oximation reaction, and synchronously reducing carbonyl and hydroxyl oxime under the catalysis of Lewis acid such as aluminum chloride in the presence of a boron metal reducing agent, so as to obtain the 2-aminoindan derivative. The invention further provides the 2-aminoindan derivative prepared by virtue of a synthetic method and a corresponding intermediate derivative. Compared with a synthetic method of the 2-aminoindan derivative in the prior art, the synthetic method disclosed by the invention has the beneficial effects that (1) only two reaction steps are adopted, and the reaction steps are obviously less than the reaction steps in the prior art; (2) the cost is relatively low, the operation is simple and convenient, and the yield is high; and (3) the preparation method is suitable for large-scale industrial production and has relatively good application prospects.