210701-08-9Relevant academic research and scientific papers
Process for producing cycloalkyl [b]benzofurans
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, (2008/06/13)
The present invention provides a process for producing an optically active compound of cycloalkyl[b]benzofuran using a readily available optically active compound as a starting material by a reaction using a transition metal or the Mitsunobu reaction, or
Synthesis of optically active cyclopenta[b]benzofuran as a precursor of m-phenyleneprostacyclin
Nishiyama, Hisao,Sakata, Naoya,Sugimoto, Hayato,Motoyama, Yukihiro,Wakita, Hisanori,Nagase, Hiroshi
, p. 930 - 932 (2007/10/03)
The optically pure cyclopenta[b]benzofuran derivatives (-)-1 and (-)-2 were synthesized from (+)-(1S,4R)-cis-4-acetoxy-2-cyclopenten-1-ol [(+)-3] via sequential Mitsunobu reaction and palladium-catalyzed allylic substitution with phenol derivatives followed by SN2′ intramolecular cyclization.
