210755-76-3

Upstream product

• 202648-25-7 phenyl 2,4,6-tri-O-Acetyl-3-O-methyl-1-seleno-β-D-glucopyranoside 
• 202648-26-8 phenyl 3-O-Methyl-1-seleno-β-D-glucopyranoside 
• 30694-94-1 2,4,6-tri-O-acetate-3-O-methyl-α-D-glucopyranosylbromide 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 210755-75-2 methyl 6-O-acetyl-4-C-(2-O-acetyl-6-O-benzyl-3-O-methyl-α-D-glucopyranosylmethyl)-4-deoxy-2,3-di-O-methyl-α-D-glucopyranoside 

Downstream Products

• 210755-77-4 (2R,3R,4R,5S,6R)-2-Benzyloxymethyl-6-[(2S,3R,4S,5R,6S)-2-(tert-butyl-dimethyl-silanyloxymethyl)-4,5,6-trimethoxy-tetrahydro-pyran-3-ylmethyl]-4-methoxy-tetrahydro-pyran-3,5-diol 
• 192505-52-5 (2S,3S,4S,5R)-3-((2R,3S,4R,5R,6R)-6-Acetoxymethyl-3,4,5-trimethoxy-tetrahydro-pyran-2-ylmethyl)-4,5-dimethoxy-6-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-2-carboxylic acid benzyl ester 
• 192505-55-8 C₄₆H₆₀Cl₃NO₁₉ 
• 210755-79-6 (2S,3S,4S,5R,6S)-3-((2R,3S,4R,5R,6R)-6-Benzyloxymethyl-3,4,5-trimethoxy-tetrahydro-pyran-2-ylmethyl)-4,5,6-trimethoxy-tetrahydro-pyran-2-carboxylic acid benzyl ester 
• 192505-51-4 [(2S,3R,4S,5R,6S)-3-((2R,3S,4R,5R,6R)-6-Benzyloxymethyl-3,4,5-trimethoxy-tetrahydro-pyran-2-ylmethyl)-4,5,6-trimethoxy-tetrahydro-pyran-2-ylmethoxy]-tert-butyl-dimethyl-silane 

Relevant academic research and scientific papers

Synthesis and biological activity of a new anti-factor Xa pentasaccharide with a C-interglycosidic bond

A mixed synthetic C, O-pentasaccharide 17 has been synthesized and shown to display an anti-factor Xa activity similar to that of the corresponding O-pentasaccharide 18. 17 represents the first example of a synthetic C-oligosaccharidic mimetic eliciting a significant biological response.

Synthesis of a C-disaccharide glycosyl donor as a key building block for the preparation of new biologically active heparin pentasaccharide mimetics

The synthesis of the C-disaccharide imidate 34, a key synthon for the synthesis of heparin pentasaccharide mimetics, is described.The C-interglycosidic bond was established through 9-endo-trig radical cyclization from two tethered monosaccharides.It was followed by conversion of the reducing end glucose unit into the required glucuronic acid derivative. - Keywords: heparin; silicon tether; radical cyclization; C-disaccharide; carbohydrate mimetics