21081-98-1Relevant academic research and scientific papers
Platinum(II) complexes containing aminophosphonate esters: Synthesis, characterization, cytotoxicity and action mechanism
Huang, Ke-Bin,Chen, Zhen-Feng,Liu, Yan-Cheng,Li, Zhu-Quan,Wei, Jian-Hua,Wang, Meng,Xie, Xiao-Li,Liang, Hong
, p. 554 - 561 (2013/07/11)
New platinum(II) complexes containing aminophosphonate ester were synthesized and fully characterized, which were found to possess better solubility in both organic solvents and water than cisplatin. These platinum(II) complexes exhibited considerable cyt
NbCl5: An efficient catalyst for one-pot synthesis of α-aminophosphonates under solvent-free conditions
Hou, Jun-Tao,Gao, Jian-Wu,Zhang, Zhan-Hui
experimental part, p. 47 - 53 (2011/09/14)
NbCl5 has been found to be a very effective catalyst for the synthesis of a variety of α-aminophosphonates through the Kabachnik-Fields reaction of carbonyl compound, amine and diethyl phosphite under solvent-free conditions. Copyright
Nano Fe3O4 as magnetically recyclable catalyst for the synthesis of α-aminophosphonates in solvent-free conditions
Reddy, B.V. Subba,Krishna, A. Siva,Ganesh,Kumar, G.G.K.S. Narayana
experimental part, p. 1359 - 1362 (2011/03/21)
The three component, one-pot synthesis of α-aminophosphonates has been achieved using super magnetic nano iron oxide at 50°C under solvent-free conditions in excellent yields. The major advantages of the present method are high yields, short reaction times, magnetically recyclable catalyst, and solvent-free reaction conditions.
Mesoporous aluminosilicate nanocage-catalyzed three-component coupling reaction: an expedient synthesis of α-aminophosphonates
Vinu, Ajayan,Kalita, Pranjal,Balasubramanian, Veerappan V.,Oveisi, Hamid,Selvan, Tamil,Mano, Ajayan,Chari, Murugulla A.,Subba Reddy
scheme or table, p. 7132 - 7136 (2010/02/27)
Here we demonstrate for the first time the synthesis of α-aminophosphonates through the three-component coupling reaction of aldehydes, amines, and diethyl phosphite by using highly acidic 3D mesoporous aluminosilicate nanocage catalyst, which gave excell
General procedure for the synthesis of α-amino phosphonates from aldehydes and ketones using indium(III) chloride as a catalyst
Ranu, Brindaban C.,Hajra, Alakananda,Jana, Umasish
, p. 1141 - 1143 (2008/02/09)
(matrix presented) (24 examples) A simple, efficient, and general method has been developed for the synthesis of α-amino phosphonates through a one-pot reaction of aldehydes and ketones with amines in the presence of indium(III) chloride as a catalyst.
The acidic cleavage of pyridylmethyl(amino)phosphonates. Formation of the corresponding amines
Boduszek, Bogdan
, p. 12483 - 12494 (2007/10/03)
Hydrolysis of 3-pyridylmethyl(amino)phosphonates by means of 20% aq. hydrochloric acid gave corresponding 3-pyridimethyl(amino)phosphonic acids, as expected. However, hydrolysis of 2- and 4-pyridylmethyl(amino)phosphonates led to decomposition of the phosphonates with a cleavage of C-P bond and formation of the corresponding amines. The leaving phosphorus moiety was identified as phosphoric acid. The scope of the reaction is limited to 2- and 4-pyridylmethyl derivatives of aminophosphonic acids and their esters, as well as to the derivatives possessing similar structure. On the contrary, the basic hydrolysis of 2- and 4-pyridylmethyl(amino)phosphonates led to the corresponding monoalkyl esters of the aminophosphonates, and no cleavage of C-P bond was observed in those cases.
