21086-80-6

Upstream product

• 13523-09-6 4-Methoxy-5-methyl-1,2-benzochinon 
• 1446354-12-6 7-methoxy-8-methyl-3,4-dihydro-2H-benzo[b]1,4-dioxepine 
• 14786-82-4 4-hydroxy-2-methylanisole 

Relevant academic research and scientific papers

An efficient strategy for protecting dihydroxyl groups of catechols

A novel strategy for protecting dihydroxyl groups of catechols has been developed. Base-mediated cyclizations of catechols with 1,3-dibromopropane provided the corresponding benzo[b]1,4-dioxepans, and herefrom the protecting group was easily cleaved by aluminum chloride. The preparation of the antibacterial and antifungal agent 4-(2-aminothiazol-4-yl)benzene-1,2-diol from catechol reliably verified its availability amenable to various harsh reaction conditions. Georg Thieme Verlag Stuttgart - New York.