2109-22-0

Basic information

• Product Name: 2-Cyclohexyl propanal
• Synonyms: 2-Cyclohexyl propanal;Cyclohexaneacetaldehyde, .alpha.-methyl-;POLLENALII;α-Methylcyclohexaneacetaldehyde
• CAS NO: 2109-22-0
• Molecular Formula: C₉H₁₆O
• Molecular Weight: 140.22274
• EINECS: 412-270-0
• Mol File: 2109-22-0.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 203°Cat760mmHg
• Flash Point: 71.4°C
• Appearance: /
• Density: 0.899g/cm³
• Vapor Pressure: 0.284mmHg at 25°C
• Refractive Index: 1.447
• CAS DataBase Reference: 2-Cyclohexyl propanal(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexyl propanal(2109-22-0)
• EPA Substance Registry System: 2-Cyclohexyl propanal(2109-22-0)

Safety Data

• Hazard Codes: Xi,N
• Statements: 43-51/53
• Safety Statements: 24-37-61
• Hazardous Substances Data: 2109-22-0(Hazardous Substances Data)

Usage

Uses

2-Cyclohexylpropanal is used as a reactant in the asymmetric synthesis of α-branched homoallylic aldehydes via Pd/chiral phosphoric acid-catalyzed direct α-allylation of α-branched aldehydes with allylic amines.

InChI:InChI=1/C9H16O/c1-8(7-10)9-5-3-2-4-6-9/h7-9H,2-6H2,1H3

Upstream product

• 2109-96-8 2-Cyclohexyl-1-methoxy-propan-2-ol 
• 2043-61-0 cyclohexanecarbaldehyde 
• 74-88-4 methyl iodide 
• 110166-46-6 2-(1-Cyclohexyl-ethyl)-benzo[1,3]dithiole 
• 4442-79-9 cyclohexylethan-1-ol 
• 7732-18-5 water 
• 201230-82-2 carbon monoxide 
• 1003-64-1 ethylidenecyclohexane 
• 5452-75-5 ethyl 2-cyclohexylacetate 
• 695-12-5 vinylcyclohexane 
• 2163-44-2 diethyl 2-cyclohexylmalonate 
• 1123-85-9 (RS)-2-phenyl-1-propanol 
• 34713-70-7 2-Phenylpropanal 
• 108-94-1 cyclohexanone 

Downstream Products

• 2037-62-9 2-Methyl-2-cyclohexyl-propandiol-(1,3) 
• 103867-68-1 (E)-2-Cyclohexyl-6-(toluene-4-sulfinyl)-hex-5-en-3-ol 
• 103867-63-6 2-Cyclohexyl-4-(toluene-4-sulfinyl)-hex-5-en-3-ol 
• 103867-73-8 (E)-5-cyclohexyl-2-hexene-1,4-diol 
• 103867-73-8 (E)-5-cyclohexyl-2-hexene-1,4-diol 
• 142505-74-6 methyl 4-cyclohexyl-3-hydroxypentanedithioate 
• 126550-41-2 cyclohexyl-2 hydroxy-3 methyl-2 pentanedithioate de methyle 
• 126550-41-2 cyclohexyl-4 hydroxy-3 methyl-2 pentanedithioate de methyle 
• 103108-15-2 anti-ethyl 4-cyclohexyl-3-hydroxydithiopentanoate 
• 103108-15-2 syn-ethyl 4-cyclohexyl-3-hydroxydithiopentanoate 
• 110874-47-0 (5R*,6R*)-6-Cyclohexyl-2,2-dimethyl-5-<(2,4,6-trimethylphenyl)thio>-3-heptanone 
• 75724-23-1 2-Cyclohexyl-pentan-3-ol 
• 114222-09-2 (2S,3R)-2-Cyclohexyl-heptan-3-ol 
• 114222-08-1 (2S,3S)-2-Cyclohexyl-heptan-3-ol 

Relevant articles and documents

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Ligand-Controlled Direct Hydroformylation of Trisubstituted Olefins

The direct hydroformylation of trisubstituted olefins has been achieved with a combination of a Rh(I) catalyst and a π-acceptor phosphorus (briphos) ligand. A sterically bulky briphos ligand with a large cone angle that forms a 1:1 complex with Rh(I) is found to be reactive for the hydroformylation of trisubstituted olefins. The aldehyde products were obtained with high diastereoselectivity (>99:1) and regioselectivity (49%-81%).

NRF2 REGULATORS

Provided are aryl analogs，pharmaceutical compositions containing them and their use as NRF2 regulators.