210917-98-9Relevant academic research and scientific papers
Anilino-monoindolylmaleimides as potent and selective JAK3 inhibitors
McDonnell, Mark E.,Bian, Haiyan,Wrobel, Jay,Smith, Garry R.,Liang, Shuguang,Ma, Haiching,Reitz, Allen B.
, p. 1116 - 1121 (2014/03/21)
We designed a series of anilino-indoylmaleimides based on structural elements from literature JAK3 inhibitors 3 and 4, and our lead 5. These new compounds were tested as inhibitors of JAKs 1, 2 and 3 and TYK2 for therapeutic intervention in rheumatoid art
Cyclic protein tyrosine kinase inhibitors
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Page 147-148, (2010/02/06)
Novel cyclic compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders.
