21102-94-3

Basic information

• Product Name: 8-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-8-azaspiro[4.5]decane-7,9-dione
• Synonyms: 8-(2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl)-8-azaspiro[4.5]decane-7,9-dione
• CAS NO: 21102-94-3
• Molecular Formula: C₂₂H₃₁N₃O₃
• Molecular Weight: 385.4998
• Mol File: 21102-94-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 585.6°C at 760 mmHg
• Flash Point: 307.9°C
• Density: 1.22g/cm³
• Vapor Pressure: 1.07E-13mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: 8-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-8-azaspiro[4.5]decane-7,9-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 8-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-8-azaspiro[4.5]decane-7,9-dione(21102-94-3)
• EPA Substance Registry System: 8-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-8-azaspiro[4.5]decane-7,9-dione(21102-94-3)

Safety Data

• Hazardous Substances Data: 21102-94-3(Hazardous Substances Data)

Upstream product

• 21098-05-5 8-(2-chloroethyl)-8-azaspiro-[4.5]decane-7,9-dione 
• 35386-24-4 1-(2-Methoxyphenyl)piperazine 
• 5662-95-3 3,3-tetramethylene glutaric anhydride 

Relevant articles and documents

Synthesis and structure-activity relationship of fluoro analogues of 8-{2-[4-(4-methoxyphenyl)piperazin-1yl]ethyl}-8-azaspiro[4.5]decane-7,9-dione as selective α1d-adrenergic receptor antagonists

We have discovered high-affinity antagonists (exemplified by 11 and 12) that are the most selective for α1d-adrenergic receptors (α1d-AR) reported to date. In cloned receptor assay systems, 12 displays at least 95-fold selectivity fo