211116-64-2Relevant academic research and scientific papers
Catalytic asymmetric synthesis of quaternary carbon centers. Exploratory investigations of intramolecular heck reactions of (E)-α,β-unsaturated 2-haloanilides and analogues to form enantioenriched spirocyclic products
Ashimori, Atsuyuki,Bachand, Benoit,Overman, Larry E.,Poon, Daniel J.
, p. 6477 - 6487 (1998)
The effect of chiral diphosphine structure, method of catalyst generation, reaction solvent, and HI scavenger on the formation of enantioenriched 3,3-disubstituted 2-oxindole 5 from asymmetric Heck cyclization of 4 was studied (eq 1). Depending upon wheth
