211134-59-7Relevant academic research and scientific papers
Asymmetric synthesis of α-substituted alkylphosphonates based on symmetrical dialkyl phosphites
Kolodiazhnyi,Grishkun,Sheiko,Demchuk,Thoennessen,Jones,Schmutzler
, p. 1568 - 1573 (2007/10/03)
Chiral C2-symmetrical dialkyl phosphites and C3-symmetrical trialkyl phosphites, derived from (-)-borneol, (-)-menthol, and 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose, were studied as the starting reagents for the preparation of chiral organophosphorus compounds. The reactions of C2-symmetrical dialkyl phosphites and C3-symmetrical trialkyl phosphites with aldehydes and amines or aldehydes are accompanied by asymmetrical induction at the α-carbon atom to yield optically active α-aminoalkylphosphonates or α-hydroxyalkylphosphonates, respectively. The stereoselectivity of the reaction depends on the structure of the starting compounds and the reaction conditions.
Chiral symmetric phosphoric acid esters as sources of optically active organophosphorus compounds
Kolodiazhnyi, Oleg I.,Grishkun, Evgen V.,Sheiko, Serge,Demchuk, Oleg,Thoennessen, Holger,Jones, Peter G.,Schmutzler, Reinhard
, p. 1645 - 1649 (2007/10/03)
Chiral symmetric di- and trialkylphosphites, derivatives of (-)-borneol, (-)-menthol and (-)-1,2:5,6-di-Oisopropylidene-α-D-glucofuranose, were studied as starting reagents for the preparation of chiral organophosphorus compounds. The reaction occurs by a
