21117-34-0

Usage

Type of compound

Triazole derivative

Potential use

Intermediate in the synthesis of pharmaceutical drugs

Biological activities

a. Antifungal
b. Anti-inflammatory
c. Anti-cancer

Application

Building block in the synthesis of various bioactive compounds

Role

Key component in the development of novel drug candidates

Potential as a ligand

For metal complexes

Upstream product

• 4971-77-1 ethyl 2-phenylethanimidoate 
• 624-84-0 formic acid hydrazide 
• 288-88-0 1,2,4-Triazole 
• 100-44-7 benzyl chloride 
• 103-80-0 phenylacetyl chloride 

Relevant academic research and scientific papers

Liquid-phase traceless synthesis of 3,5-disubstituted 1,2,4-triazoles

A liquid-phase traceless route to 3,5-disubstituted-1,2,4-triazoles has been developed, which allows for the incorporation of two elements of diversity. The heterocycle was constructed upon PEG6000 (soluble polymer) modified by 4-hydroxy-2-methoxy-benzaldehyde, from which a traceless cleavage could be realized with TFA-CH2Cl2. This method provided a library of 3,5-disubstituted-1,2,4-triazoles with high yields and purity. Georg Thieme Verlag Stuttgart.

Diarylacetylenes, enamines and acetylenic polymers and their production

Diarylacetylenes and diarylenamines are synthesized from a Schiff's base and an N-arylmethylheterocycle; these compounds are useful as intermediates for a variety of polymers; in particular an efficient process is provided for producing diaryl acetylenes useful in the efficient production of acetylene group-containing polymers which can be cross-linked to produce high strength polymers free of structural defects such as conventionally arise as a result of liberation of volatiles during the cross-linking.