2113-88-4

Basic information

• Product Name: 4-acetyl-5-hydroxy-2-(2-methylpropyl)-1,2-dihydro-3H-pyrrol-3-one
• CAS NO: 2113-88-4
• Molecular Formula: C₁₀H₁₅NO₃
• Molecular Weight: 197.231
• Mol File: 2113-88-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 327.4°C at 760 mmHg
• Flash Point: 151.8°C
• Density: 1.162g/cm³
• Vapor Pressure: 1.54E-05mmHg at 25°C
• Refractive Index: 1.511
• CAS DataBase Reference: 4-acetyl-5-hydroxy-2-(2-methylpropyl)-1,2-dihydro-3H-pyrrol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-acetyl-5-hydroxy-2-(2-methylpropyl)-1,2-dihydro-3H-pyrrol-3-one(2113-88-4)
• EPA Substance Registry System: 4-acetyl-5-hydroxy-2-(2-methylpropyl)-1,2-dihydro-3H-pyrrol-3-one(2113-88-4)

Safety Data

• Hazardous Substances Data: 2113-88-4(Hazardous Substances Data)

Upstream product

• 62972-97-8 methyl 2-[N-(1,3-dioxobutyl)amino]-4-methylpentanoate 
• 6322-53-8 leucine methyl ester hydrochloride 
• 7517-19-3 methyl (L)-leucinate hydrochloride 
• 62972-97-8 Methyl N-acetoacetyl-L-leucinate 

Relevant articles and documents

3-hydrazido and 3-hydrazono derivatives of tenuazonic acid and their herbicide evaluation

With the aim of optimizing the structure of tenuazonic acid and improving the herbicidal activity, hydrazine moieties were introduced to the 3-position of pyrrolidine-2,4-dione scaffold of tenuazonic acid. 3-Hydrazido-pyrrolidine-2,4- dione compounds (4a, 4b, 4c, 4d, 4e) were prepared from corresponding carboxylates and hydrazines via a microwave-assisted amidation, whereas 3-hydrazono compounds (7a, 7b, 7c, 7d, 7e) were prepared from corresponding 3-acetyl pyrrolidine-2,4-dione. Both of the two structures also exhibited herbicidal activities, especially against the dicotyledonous species amaranth pigweed (Amaranthus retroflexus), but with different structure-activity relationship.

Studies on antiviral agents. 3. Synthesis of tenuazonic acid derivatives.

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