2113-93-1

Basic information

• Product Name: 3-acetyltetramic acid
• Synonyms: 3-acetyltetramic acid;3-Acetyl-1,5-dihydro-4-hydroxy-2H-pyrrol-2-one;3-Acetyl-4-hydroxy-1,5-dihydro-2H-pyrrole-2-one
• CAS NO: 2113-93-1
• Molecular Formula: C6H7 N O3
• Molecular Weight: 141.12
• Mol File: 2113-93-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 303.2°Cat760mmHg
• Flash Point: 137.2°C
• Appearance: /
• Density: 1.428g/cm³
• Vapor Pressure: 9.07E-05mmHg at 25°C
• Refractive Index: 1.568
• CAS DataBase Reference: 3-acetyltetramic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-acetyltetramic acid(2113-93-1)
• EPA Substance Registry System: 3-acetyltetramic acid(2113-93-1)

Safety Data

• Hazardous Substances Data: 2113-93-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H7NO3/c1-3(8)5-4(9)2-7-6(5)10/h7,10H,2H2,1H3

Upstream product

• 140707-03-5 (3-oxobutyryl)glycine methyl ester 
• 105688-27-5 2-Acetyl-4-acetylamino-3-oxo-butyric acid ethyl ester 
• 105688-26-4 2-Acetyl-4-acetylamino-3-oxo-butyric acid methyl ester 
• 105702-03-2 N,3-acetyl-4-hydroxypyrrolin-2-one 
• 53587-10-3 hippuryl chloride 
• 141-97-9 ethyl acetoacetate 
• 19206-94-1 ethyl-N-(3-oxobutanoyl)glycinate 

Downstream Products

• 1262232-42-7 (Z)-3-acetyl-4-hydroxy-5-(4-methoxybenzylidene)-pyrrolidine-2-one 
• 1262232-43-8 (Z)-3-acetyl-5-(2-chlorobenzylidene)-4-hydroxypyrrolidine-2-one 
• 1262232-44-9 (Z)-3-acetyl-5-(4-chlorobenzylidene)-4-hydroxypyrrolidine-2-one 

Relevant articles and documents

Amic acid derivative as well as preparation method and application thereof

The invention provides an amine acid derivative as well as a preparation method and application thereof. The amine acid derivative has the structure as follows. Herein, R is selected from methyl, methoxy and the like. R1 Selected from C1 - C4 a

Synthesis, characterization, and biological activities of novel (Z)-3-((E)-1-(alkyloxyimino)ethyl)-5-arylidene-4-hydroxypyrroline-2-one derivatives

Twenty-four novel tetramic acid derivatives (Z)-3-((E)-1-(alkyloxyimino) ethyl)-5-arylidene-4-hydroxypyrroline-2-ones 6a-x were synthesized by the reaction of (Z)-3-acetyl-5-arylidene-4-hydroxypyrroline-2-ones 4 with O-alkyl hydroxylamines 5 under reflux conditions in good yields (77.2-92.4%). Their structures were confirmed by IR, 1H-NMR, MS, and elemental analysis. The preliminary bioassays showed that most of the title compounds exhibited noticeable fungicidal activities against Colletotrichumorbiculare and a certain degree of fungicidal activities against Fusarium gramineaum and Rhizoctonia cerealis at a concentration of 100 μg/mL.

Acylaminoacetyl Derivatives of Active Methylene Compounds. 2. The Cyclization of the Acetylaminoacetyl Derivatives to α-Substituted Tetramic Acids and the Formation of N-Acetyl-α-substituted Tetramic Acids

The reaction of aceturic acid p-nitrophenyl ester with active methylene compounds Y-CH2-CO2R has been found to give either the normally expected C-acylation compounds 2 (Y = -CN, -CO2R, -COCH3) or N-acetyl-α-Y-substituted tetramic acids 3 (Y = -CO2R, -COC