53587-10-3

Upstream product

• 495-69-2 Hippuric Acid 
• 75-36-5 acetyl chloride 
• 10026-13-8 phosphorus pentachloride 

Downstream Products

• 94359-88-3 hippuric acid isopentylamide 
• 20806-84-2 N-(N-benzoyl-glycyl)-leucine ethyl ester 
• 873977-89-0 hippuric acid-(2-hydroxy-1,2,2-triphenyl-ethylamide) 
• 38051-21-7 N,N'-dibenzoylpiperazine-2,5-dione 
• 861612-40-0 4-benzoylamino-2-cyano-acetoacetic acid ethyl ester 
• 83544-52-9 ethyl hippurylmalonate 
• 412017-27-7 N-(2-ethyl-2-hydroxy-butyl)-benzamide 
• 5813-81-0 hippuramide 
• 109068-48-6 N-(N-benzoyl-glycyl)-L-tyrosine 
• 138506-49-7 hippuric acid-(4-hydroxy-phenyl ester) 
• 2979-55-7 N-benzoylglycine ethyl thiol ester 

Relevant academic research and scientific papers

2,5-diphenyl-oxazole preparation method

The invention relates to a method for preparing scintillation pure grade 2,5-diphenyl oxazole (DPO or PPO for short). The method comprises the following steps: by taking benzoyl glycine as a raw material, performing multiple steps of reaction such as acylating chlorination, Frieldel-Crafts and ring formation, purifying middle products of each step without being separated, and preparing 2,5-diphenyl oxazole by using a one-pot method. An obtained product can be rectified and purified, the requirements of a scintillator cannot be met but metal oxide heating treatment is needed, and thus a 2,5-diphenyl oxazole product for scintillation fluor can be obtained. As the one-pot method is adopted to prepare 2,5-diphenyl oxazole, the reaction steps are reduced, the operation process is simplified, the production efficiency is improved, a purification method is simple, convenient and effective, and on-scale industrialization production is achieved.

Synthesis of dipeptides using polymer bound hydroxamic esters - A comparative study of reactivity

Poly(Methyl methaery late) and polystyrene supported hydroxamic esters have been prepared and developed as a new class of recyclable solid phase acylating reagents for the synthesis of peptides. The crosslinking agents used are DVB (divinyl benzene). EGDM

SYNTHESIS OF LUMINOPHORIC DERIVATIVES OF PBD BASED ON 2,5-DIARYL SUBSTITUTED THIAZOLES AND OXAZOLES

The Friedel-Crafts acylation of 2-(biphenyl-4-yl)-5-phenyl-1,3,4-oxadiazole (PBD) with hippuryl chloride has been used to prepare the derivative V which on cyclization with POCl3 or P4S10 gives the respective oxazole (or thiazole) derivative of PBD, XIa or XIb.The reaction of carboxylic acid II with 4-(ω-aminoacetyl)biphenyl in the presence of CDI gives N-acyl-α-aminoketone VII; the analogous compound VI has been prepared by acylating ω-aminoacetophenone with acyl chloride III.The cyclization of these compounds gives bifluorophores Xa - Xd.

Process for the preparation of 2-(2-thienyl)-ethylamine and derivatives thereof

The present invention provides a process for the preparation of 2-(2-thienyl)-ethylamine and derivatives thereof having the general formula: STR1 wherein R1 and R2 are hydrogen or taken together form a phenyl ring.

Acylaminoacetyl Derivatives of Active Methylene Compounds. 1. The Cyclization of the Benzoylaminoacetyl Derivatives to α-Substituted Tetramic Acids (1)

Hippuric acid was converted to α-Y-substituted tetramic acids (Y = -CN, -CO2R and -COCH3) according to the following general scheme of reactions: a) preparation of the hippuric acid chloride or of its p-nitrophenyl ester; b) C-acylation of an active methy