211301-15-4Relevant academic research and scientific papers
Bis-substituted malonic acid hydroxamate derivatives as inhibitors of human neutrophil collagenase (MMP8)
Graf Von Roedern, Erich,Brandstetter, Hans,Engh, Richard A.,Bode, Wolfram,Grams, Frank,Moroder, Luis
, p. 3041 - 3047 (2007/10/03)
Malonic acid hydroxamate derivatives bis-substituted at the methylene group were synthesized as potential nonpeptidic inhibitors of human neutrophil collagenase (MMP8). The presence of an aromatic residue both at the C2 malonic acid position and in the C-
