211316-05-1

Basic information

• Product Name: (2S,3aS,4aS,5R,8S,8aR)-2-{[(phenylmethyl)oxy]methyl}-2,5,10,10-tetramethyl-5,8-methanooctahydro-2H-isoxazolo[3,2-b]benzoxazole
• Synonyms: (2S,3aS,4aS,5R,8S,8aR)-2-{[(phenylmethyl)oxy]methyl}-2,5,10,10-tetramethyl-5,8-methanooctahydro-2H-isoxazolo[3,2-b]benzoxazole
• CAS NO: 211316-05-1
• Molecular Weight: 357.493
• Mol File: 211316-05-1.mol

Chemical Properties

• CAS DataBase Reference: (2S,3aS,4aS,5R,8S,8aR)-2-{[(phenylmethyl)oxy]methyl}-2,5,10,10-tetramethyl-5,8-methanooctahydro-2H-isoxazolo[3,2-b]benzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3aS,4aS,5R,8S,8aR)-2-{[(phenylmethyl)oxy]methyl}-2,5,10,10-tetramethyl-5,8-methanooctahydro-2H-isoxazolo[3,2-b]benzoxazole(211316-05-1)
• EPA Substance Registry System: (2S,3aS,4aS,5R,8S,8aR)-2-{[(phenylmethyl)oxy]methyl}-2,5,10,10-tetramethyl-5,8-methanooctahydro-2H-isoxazolo[3,2-b]benzoxazole(211316-05-1)

Safety Data

• Hazardous Substances Data: 211316-05-1(Hazardous Substances Data)

Upstream product

• 211316-00-6 (2S,3aS,4aS,5R,8S,8aR)-2,5,10,10-tetramethyl-5,8-methanooctahydro-2H-isoxazolo[3,2-b]benzoxazole-2-carboxylic acid methyl ester 
• 100-39-0 benzyl bromide 
• 211316-04-0 (2S,3aS,4aS,5R,8S,8aR)-2-(hydroxymethyl)-2,5,10,10-tetramethyl-5,8-methanooctahydro-2H-isoxazolo[3,2-b]benzoxazole 

Downstream Products

• 211316-08-4 (E)-(S)-7-Benzyloxy-6-hydroxy-6-methyl-hept-3-en-2-one 
• 211316-07-3 (S)-4-Benzyloxy-3-hydroxy-3-methyl-butyraldehyde 

Relevant articles and documents

[3 + 2] Cycloadditions between α,β-Unsaturated Esters or Nitroalkenes and Camphor-Derived Oxazoline N-Oxides: Experimental and Theoretical Study

Oxazoline N-oxide 2 in the presence of α,β-unsaturated esters or nitroalkenes afforded the corresponding adducts with excellent regio- and stereoselectivities depending of the substitution pattern on the dipolarophile. Especially, inversion of regioselectivity was observed by switching from a 1,2-disubstituted to a 1,1-disubstituted α,β-unsaturated ester. This was not observed when nitroalkenes are used as dipolarophiles. An attempt to rationalize the observed selectivities by semiempirical calculations at RHF AM1 level is described. The cycloadduct 5e has been used as the starting material in a total synthesis of the pheromone (-)-frontalin 12.