21134-98-5

Usage

Type of compound

Heterocyclic organic compound

Structure

Six-membered ring with three nitrogen atoms and three carbon atoms

Industry use

Pharmaceutical industry as a building block for various organic compounds

Biological activity

Potential therapeutic agent for diseases such as cancer and Alzheimer's

Application in coordination chemistry

Used as a ligand

Application in biochemical research

Used as a fluorescent probe

Versatility

Potential applications in various fields due to unique structure and properties

Upstream product

• 942-72-3 3-amino-6-phenyl-1,2,4-triazine 
• 33859-68-6 6-Phenyl-1,2,4-triazine N-oxide 

Downstream Products

• 15969-31-0 5-Amino-6-phenyl-1,2,4-triazine 
• 114468-24-5 C₁₈H₁₇ClN₃O₂S^(1-)*K⁽¹⁺⁾ 
• 87505-18-8 5-(phenylsulfonyl)methyl-6-phenyl-1,2,4-triazine 
• 151724-25-3 4-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridine 

Relevant academic research and scientific papers

Imidazo-triazine derivatives as ligands for GABA receptors

A class of substituted 1,2,4-triazolo[4,3-]pyridazine derivatives, possessing an optionally substituted cycloalkyl, phenyl or heteroaryl substituent at the 3-position, a substituted alkoxy moiety at the 6-position, and an optionally substituted bicycloalkyl ring system at the 7-position, are selective ligands for GABAAreceptors, in particular having high affinity for the α2 and/or α3 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.

Deamination of 2-aminothiazoles and 3-amino-1,2,4-triazines with nitric oxide in the presence of a catalytic amount of oxygen

2-Aminothiazoles, 2-aminobenzazoles, and 3-amino-1,2,4-triazines were deaminated using nitric oxide (NO) in the presence of a catalytic amount of oxygen to afford corresponding unsubstituted heterocycles in good yields.

ELECTRONIC SPECTRA OF asym-TRIAZINYL GROUPS

The induction, resonance, and Hammett constants of 3-, 5-, and 6-asym-triazinyl groups were calculated from the data of 1H, 13C, 19F NMR spectra of isomeric aminophenyl-, hydroxyphenyl-, phenyl-, and fluorophenyl-asym-triazines.