33859-68-6Relevant academic research and scientific papers
Regioselectivity of nucleophilic attack on the reactions of 1,2,4-triazine 4-oxides with certain C-nucleophiles
Kozhevnikov,Prokhorov,Rusinov,Chupakhin
, p. 911 - 915 (2007/10/03)
The addition of CH-active compounds to 6-aryl-1,2,4-triazine 4-oxide is reversible and occurs under conditions of kinetic control at position 5 of the heterocycle to form cyclic C(5)-σH adducts. Under conditions of thermodynamic control the nuc
Imidazo-triazine derivatives as ligands for GABA receptors
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, (2008/06/13)
A class of substituted 1,2,4-triazolo[4,3-]pyridazine derivatives, possessing an optionally substituted cycloalkyl, phenyl or heteroaryl substituent at the 3-position, a substituted alkoxy moiety at the 6-position, and an optionally substituted bicycloalkyl ring system at the 7-position, are selective ligands for GABAAreceptors, in particular having high affinity for the α2 and/or α3 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.
Ring-Chain Transformations of 4-Hydroxy-3,4-dihydro-1,2,4-triazines. New Synthesis of 1,2,4-Triazine 4-Oxides
Kozhevnikov,Kozhevnikov,Rusinov,Chupakhin,Sidorov,Klyuev
, p. 393 - 399 (2007/10/03)
Ring-chain transformations in solution and in the gas phase of the condensation products of isonitrosoacetophenone and isonitrosoacelone hydrazones with aldehydes and ketones were studied by 1H NMR spectroscopy and mass spectrometry. A new meth
