211363-59-6 Usage
Description
(E)-N-[2-Chloro-2-phenyl-1-(piperidin-1-ylcarbonyl)vinyl]benzamide is a complex organic compound belonging to the benzamides class, characterized by the presence of a carboxamido group attached to a benzene ring. (E)-N-[2-Chloro-2-phenyl-1-(piperidin-1-ylcarbonyl)vinyl]benzamide features a piperidine ring, a vinyl group, and a benzene ring, along with a chlorine atom and a carbonyl group. Its unique structure and properties make it a valuable candidate for chemical research and potential applications in the pharmaceutical industry for drug development.
Uses
Used in Chemical Research:
(E)-N-[2-Chloro-2-phenyl-1-(piperidin-1-ylcarbonyl)vinyl]benzamide is used as a research compound for studying its chemical properties and behavior in various chemical contexts. Its complex structure allows scientists to explore its reactivity, stability, and potential interactions with other molecules.
Used in Pharmaceutical Industry:
(E)-N-[2-Chloro-2-phenyl-1-(piperidin-1-ylcarbonyl)vinyl]benzamide is used as a starting material or intermediate in the synthesis of new drugs. Its unique structure and functional groups can be further modified or combined with other compounds to develop potential therapeutic agents with specific pharmacological properties.
Used in Drug Design and Development:
(E)-N-[2-Chloro-2-phenyl-1-(piperidin-1-ylcarbonyl)vinyl]benzamide is used as a lead compound in drug design and development. Its structure can be optimized and fine-tuned to improve its pharmacokinetic and pharmacodynamic properties, such as absorption, distribution, metabolism, excretion, and toxicity (ADMET) profiles. (E)-N-[2-Chloro-2-phenyl-1-(piperidin-1-ylcarbonyl)vinyl]benzamide may serve as a basis for the development of new drugs targeting various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 211363-59-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,1,3,6 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 211363-59:
(8*2)+(7*1)+(6*1)+(5*3)+(4*6)+(3*3)+(2*5)+(1*9)=96
96 % 10 = 6
So 211363-59-6 is a valid CAS Registry Number.
211363-59-6Relevant articles and documents
Synthesis and quantitative structure-activity relationships study for phenylpropenamide derivatives as inhibitors of hepatitis B virus replication
Yang, Jing,Ma, Min,Wang, Xue-Ding,Jiang, Xing-Jun,Zhang, Yuan-Yuan,Yang, Wei-Qing,Li, Zi-Cheng,Wang, Xi-Hong,Yang, Bin,Ma, Meng-Lin
, p. 82 - 91 (2015/07/27)
A series of new phenylpropenamide derivatives containing different substituents was synthesized, characterized and evaluated for their anti-hepatitis B virus (HBV) activities. The quantitative structure eactivity relationships (QSAR) of phenylpropenamide compound have been studied. The 2D-QSAR models, based on DFT and multiple linear regression analysis methods, revealed that higher values of total energy (TE) and lower entropy (Sθ) enhanced the anti-HBV activities of the phenylpropenamide molecules. Predictive 3D-QSAR models were established using SYBYL multifit molecular alignment rule. The optimum models were all statistically significant with cross-validated and conventional coefficients, indicating that they were reliable enough for activity prediction.
2-SUBSTITUTED-3-PROPENAMIDE DERIVATIVES AND METHODS OF USING THE SAME
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Page 56-57, (2010/02/07)
This invention provides 2-substituted-propenamide derivatives and their compositions for the treament of hepatitis B virus and/or hepatitis D virus.
