21139-63-9

Usage

Physical state

White solid

Usage

Synthesis of various pharmaceuticals and agrochemicals

Chemical class

Pyrimidine derivatives (building blocks for new drugs)

Unique chemical properties

Presence of chlorophenyl and dichloropyrimidine groups

Research tool

Biological and pharmacological activities study

Importance

Diverse applications in pharmaceutical and agrochemical industries

Upstream product

• 26863-50-3 2-(3-chloro-phenyl)-1H-pyrimidine-4,6-dione 
• 24095-60-1 3-chlorobenzenecarboximidamide hydrochloride 

Relevant academic research and scientific papers

Organic compound with nitrogen-containing spiro structure, and application thereof and organic electroluminescent device

The invention relates to the field of organic electroluminescent devices, and discloses an organic compound with a nitrogen-containing spiro structure, and application thereof, and an organic electroluminescent device, wherein the compound has a structure represented by a formula (I). When the organic compound with the nitrogen-containing spiro structure is used in an organic electroluminescent device, the organic compound has relatively low driving voltage, relatively high current efficiency and relatively long service life.

BIARYL PIPERAZINYL-PYRIDINE ANALOGUES

Biaryl piperazinyl -pyri dine analogues are provided, of the Formula (I): wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands, for receptor localization studies.

Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants

This invention is directed to aryl and heterocyclyl substituted pyrimidine derivatives selected from the following formulae: wherein Z1, Z2, R1, R2, R3, R4, R5and R6are defined herein. These compounds are useful as anti-coagulants.

Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants

This invention is directed to aryl and heterocyclyl substituted pyrimidine derivatives selected from the following formulae: wherein Z1, Z2, R1, R2, R3, R4, R5 and R6 are defined herein. These compounds are useful as anti-coagulants.

4-Amino-2-phenyl-6-thiopryimidines

The invention is directed to 4-amino-2-phenyl-6-thiopyrimidine compounds having the formula SPC1 Where R1 -R3 are as defined in the specification. The compounds have pharmacodynamic activity as central nervous system depressants. That is, they produce a calming effect in the host.