21144-93-4 Usage
Molecular Weight
229.28 g/mol
Structure
2-(3,4-Dihydro-1H-carbazol-9(2H)-yl)acetic acid has a carbazole core structure with a carboxylic acid group attached to the ethyl chain at the 2nd position.
Pharmacological Properties
2-(3,4-Dihydro-1H-carbazol-9(2H)-yl)acetic acid has potential pharmacological properties such as antihypertensive, anti-inflammatory, and antioxidant activities.
Therapeutic Applications
It has been studied for its potential use in the treatment of neurodegenerative diseases and as a component in organic electronics.
Chemical Derivation
It is derived from carbazole, a heterocyclic aromatic compound.
Unique Platform
The chemical structure of 2-(3,4-Dihydro-1H-carbazol-9(2H)-yl)acetic acid provides a unique platform for further research and development of novel pharmaceuticals and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 21144-93-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,1,4 and 4 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 21144-93:
(7*2)+(6*1)+(5*1)+(4*4)+(3*4)+(2*9)+(1*3)=74
74 % 10 = 4
So 21144-93-4 is a valid CAS Registry Number.
21144-93-4Relevant articles and documents
ACIDIC PROPERTIES OF N-HETARYLACETIC ACIDS AND INDUCTIVE CONSTANTS OF N-HETARYL SUBSTITUENTS
Filippova, T. A.,Sukhoroslova, M. M.,Lopatinskii, V. P.,Filimonov, V. D.
, p. 300 - 303 (1983)
The inductive constants of the corresponding heterocyclic fragments were calculated on the basis of data on the pKa values obtained by potentiometric titration of derivatives of indole, carbazole, 3-methylcarbazole, tetrahydrocarbazole, 6-methyltetrahydrocarbazole, and phenothiazine.The ?0R constant of the 9-carbazolyl group was also calculated.The enthalpy and entropy of acidic dissociation were calculated from data on the effect of temperature on the pKa of 9-carbazolylacetic acid.It is shown that the entropy contribution to the free energy of dissociation of 9-carbazolylacetic acid predominates.
