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50270-60-5

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50270-60-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 50270-60-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,2,7 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 50270-60:
(7*5)+(6*0)+(5*2)+(4*7)+(3*0)+(2*6)+(1*0)=85
85 % 10 = 5
So 50270-60-5 is a valid CAS Registry Number.

50270-60-5Relevant articles and documents

2,3,4,9-TETRAHYDRO-1H-CARBAZOLE DERIVATIVES AS CRTH2 RECEPTOR ANTAGONISTS

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Page/Page column 51, (2008/06/13)

The invention relates to novel tetrahydro-lH-carbazole derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and methods of treatment comprising administration of said compounds to patients.

Synthesis and pharmacological evaluation of 2,3-dialkylindoles, 'in vitro' inhibitors of thrombin-induced platelet aggregation

Arcari,Aveta,Brandt,Cecchetelli,Corsi,Solinas

, p. 405 - 425 (2007/10/02)

A series of 2,3-dialkylindoles (1-5) have been prepared and tested as antithrombotic agents. The whole class showed in vitro interesting activity in the inhibition of thrombin-induced aggregation. Among these compounds some ones showed activity comparable to standards also in the inhibition of collagen-induced aggregation. Owing to a very fast metabolic degradation through a beta-oxidative mechanism, a drastic decrease of activity in several tests ex vivo or in vivo was observed.

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