21148-24-3

Basic information

• Product Name: (+/-)-threo-1-chloro-2-phenyl-1,2-d2 ethane
• CAS NO: 21148-24-3
• Molecular Weight: 142.597
• Mol File: 21148-24-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (+/-)-threo-1-chloro-2-phenyl-1,2-d2 ethane(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-threo-1-chloro-2-phenyl-1,2-d2 ethane(21148-24-3)
• EPA Substance Registry System: (+/-)-threo-1-chloro-2-phenyl-1,2-d2 ethane(21148-24-3)

Safety Data

• Hazardous Substances Data: 21148-24-3(Hazardous Substances Data)

Upstream product

• 67213-45-0 2-phenylethanol-1,2-d₂ 
• 1517-53-9 (E)-ethene-1,2-d2 
• 100-56-1 phenylmercury(II) chloride 

Downstream Products

• 52751-12-9 trans-α,β-dideuteriostyrene 
• 52751-11-8 cis<α,β-2H2>styrene 
• 21370-59-2 (Z)-β-deuteriostyrene 
• 6911-81-5 (E)-β-deuteriostyrene 

Relevant articles and documents

Using secondary alpha deuterium kinetic isotope effects to determine the stereochemistry of an E2 reaction; the stereochemistry of the E2 reaction of 1-chloro-2-phenylethane with potassium tert-butoxide in tert-butyl alcohol

Isotopic labelling studies have shown that the E2 reaction of 1-chloro-2-phenylethane with potassium tert-butoxide in tert-butyl alcohol occurs via an anti-periplanar stereochemistry. This demonstrates that the different secondary alpha deuterium kinetic isotope effects found for the high and low base concentrations and in the presence of 18-crown-6 ether are because of changes in transition state structure that occur when the form of the reacting base changes rather than to a change in the stereochemistry of the reaction.