211561-61-4Relevant academic research and scientific papers
1,2,3-Diheterocyclization reactions on the allenylidene ligand of a ruthenium complex
Esteruelas, Miguel A.,Gómez, Angel V.,López, Ana M.,O?ate, Enrique
, p. 3567 - 3573 (2008/10/08)
The allenylidene complex [Ru(η5-C5H5)(C=C=CPh 2)(CO)(PPri3)]BF4 (1) reacts with pyrazole to afford [Ru(η5-C5H5){C=CHC(Ph) 2N(CH)3N}(CO)(PPri3)]BF4 (2) as a result of the addition of pyrazole to the allenylidene of 1. The structure of 2 was determined by an X-ray investigation, revealing a Ru-C(bicycle) distance of 2.073(4) A?. Treatment of 2 with sodium methoxide deprotonates the bicycle, which also undergoes an opening process to give the functionalized alkynyl derivative Ru(η5-C5H5){CC(Ph)2N(CH) 3N}(CO)PPri3) (3). The reactions of 1 with 3,5-dimethylpyrazole and 3-methylpyrazole lead to [Ru(η5-C5H5)-{C=CHC(Ph) 2NC(R)CHC(CH3)N}(CO)(PPri3)]BF 4 (R = CH3 (8), H (9)). In the presence of sodium methoxide, complex 9 affords Ru(η5-C5H5){C=CC(Ph)2N(CH) 2C(CH3)N}(CO)PPri3) (10). The allenylidene ligand of 1 also adds pyridine-2-thiol. In this case, the reaction product is [Ru(η5-C5H5){C=CHC(Ph) 2N(CH)4CS}(CO)(PPri3)]BF4 (11), which yields the allenyl derivative Ru(η5-C5H5){C[SC(CH) 4N]=C=CPh2}(CO)(PPri3) (12) by reaction with sodium methoxide.
