211565-43-4Relevant academic research and scientific papers
The use of phosphinamide N-protecting groups in the diastereoselective reduction of ketones
Palmer, Matthew J.,Studley, John R.,Walsgrove, Tim C.,Wills, Martin
, p. 8827 - 8840 (2007/10/03)
The phosphinamide N-protecting group is demonstrated to be an effective directing group for diastereoselective reductions of proximal ketones. A range of methods for the preparation of the requisite α-amino ketones substrates are described.
