2116-64-5

Basic information

• Product Name: 4-phenethylpyridine
• Synonyms: 4-phenethylpyridine;Pyridine, 4-(2-phenylethyl)-
• CAS NO: 2116-64-5
• Molecular Formula: C₁₃H₁₃N
• Molecular Weight: 183.25
• Mol File: 2116-64-5.mol
• Article Data: 30

Chemical Properties

• Boiling Point: 283.2 °C at 760 mmHg
• Flash Point: 116.2 °C
• Appearance: /
• Density: 1.04 g/cm³
• Vapor Pressure: 0.00547mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: 4-phenethylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenethylpyridine(2116-64-5)
• EPA Substance Registry System: 4-phenethylpyridine(2116-64-5)

Safety Data

• Hazardous Substances Data: 2116-64-5(Hazardous Substances Data)

Usage

General Description

4-Phenethylpyridine is a chemical compound with the molecular formula C13H13N. It is an organic compound that consists of a pyridine ring with a phenethyl group attached to it. 4-phenethylpyridine is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a flavoring agent in food products. 4-Phenethylpyridine is known for its strong odor and is a potential irritant to the eyes, skin, and respiratory system. It is important to handle this compound with caution and follow proper safety protocols when working with it.

InChI:InChI=1/C13H13N/c1-2-4-12(5-3-1)6-7-13-8-10-14-11-9-13/h1-5,8-11H,6-7H2

Upstream product

• 108-89-4 picoline 
• 100-44-7 benzyl chloride 
• 2785-29-7 benzyl potassium 
• 100-51-6 benzyl alcohol 
• 6844-47-9 4-[(trimethylsilanyl)methyl]-pyridine 
• 100-39-0 benzyl bromide 
• 110-86-1 pyridine 
• 181219-01-2 4-pyridineboronic acid pinacol ester 
• 59137-44-9 3-carboxy-2-(pyridin-1-ium-1-yl)propanoate 
• 100-48-1 pyridine-4-carbonitrile 
• 84379-71-5 1,3-dioxoisoindolin-2-yl 3-phenylpropanoate 
• 13258-63-4 4-(2-Aminoethyl)pyridine 
• 108-86-1 bromobenzene 
• 13295-94-8 4-(phenylethynyl)pyridine 

Downstream Products

• 38025-43-3 1-benzyl-4-(2-phenylethyl)-1,2,3,6-tetrahydropyridine 
• 161772-58-3 Re(CO)3(C₁₂H₈N₂)(C₁₃H₁₃N)⁽¹⁺⁾*ClO₄^(1-) = [Re(CO)3(C₁₂H₈N₂)(C₁₃H₁₃N)]ClO₄ 
• 161772-56-1 Re(CO)3(C₁₀N₂H₈)C₅NH₄CH₂CH₂C₆H₅⁽¹⁺⁾*ClO₄^(1-)=Re(CO)3(C₁₀N₂H₈)C₅NH₄CH₂CH₂C₆H₅(ClO₄) 
• 1352558-62-3 4,4-bis(2-phenylethyl)-1-triisopropylsilyl-1,4-dihydropyridine 
• 1352558-89-4 4,4-bis(2-phenylethyl)piperidine-cis-2,6-dicarboxylic acid hydrochloride 
• 1352558-84-9 4,4-bis(2-phenylethyl)piperidine-2-carboxylic acid hydrochloride 
• 1352558-81-6 4,4-bis(2-phenylethyl)piperidine-2-carbonitrile 
• 1352558-78-1 1-acetyl-4,4-bis(2-phenylethyl)-1,2,3,4-tetrahydropyridine-2-carbonitrile 
• 1352558-75-8 4,4-bis(2-phenylethyl)-1-triisopropylsilyl-1,2,3,4-tetrahydropyridine-2-carbonitrile 
• 1352558-72-5 4,4-bis(2-phenylethyl)-1-triisopropylsilylpiperidine-cis-2,6-dicarbonitrile 
• 1352558-67-8 4,4-bis(2-phenylethyl)piperidine-2,6-dicarbonitrile 
• 127781-77-5 1-Methyl-4-(2-phenylethyl)-pyridiniumiodid 
• 6318-70-3 4-(2-[4]pyridyl-ethyl)-aniline 
• 85333-29-5 2-methyl-7-(2-phenylethyl)-imidazo[1,2-a]pyridine 

Relevant articles and documents

Catalytic reduction of an α,β-disubstituted alkene with sodium borohydride in the presence of tetra-tert-butylphthalocyanine complexes

Cobalt tetra-tert-butylphthalocyanine was found an efficient catalyst for the catalytic reduction of 4-[(E)-2-phenylethenyl]-pyridine to 4-(2-phenylethyl)pyridine with sodium borohydride.

Iridium-Catalyzed C-Alkylation of Methyl Group on N-Heteroaromatic Compounds using Alcohols

In this study, we developed a catalytic system for the C-alkylation of a methyl group on N-heteroaromatic compounds, including pyridine, pyrimidine, pyrazine, quinoline, quinoxaline, and isoquinoline, using alcohols based on a hydrogen-borrowing process with [Cp*IrCl2]2 (Cp*: η5-pentamethylcyclopentadienyl) combined with potassium t-butoxide and 18-crown-6-ether as the catalyst precursor.

Chemoselective Hydrogenation of Alkynes to (Z) -Alkenes Using an Air-Stable Base Metal Catalyst

A highly selective hydrogenation of alkynes using an air-stable and readily available manganese catalyst has been achieved. The reaction proceeds under mild reaction conditions and tolerates various functional groups, resulting in (Z)-alkenes and allylic alcohols in high yields. Mechanistic experiments suggest that the reaction proceeds via a bifunctional activation involving metal-ligand cooperativity.