211676-20-9Relevant academic research and scientific papers
Stabilization of Hoogsteen base pairing by introduction of NH2 group at the C8 position of adenine
Kawai, Kiyohiko,Saito, Isao,Sugiyama, Hiroshi
, p. 5221 - 5224 (1998)
The synthesis of 8-aminodeoxyadenosine containing oligonucleotides has been described. The incorporation of an amino group at the C8 position of adenine greatly stabilized the Hoogsteen base pairing in triplex formation.
