Stabilization of Hoogsteen base pairing by introduction of NH2 group at the C8 position of adenine

DOI: 10.1016/S0040-4039(98)01026-0

Source and publish data:

Tetrahedron Letters p. 5221 - 5224 (1998)

Update date:2022-08-03

Topics:

Authors:

Kawai, Kiyohiko

Saito, Isao

Sugiyama, Hiroshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(98)01026-0

The synthesis of 8-aminodeoxyadenosine containing oligonucleotides has been described. The incorporation of an amino group at the C8 position of adenine greatly stabilized the Hoogsteen base pairing in triplex formation.

Full text of DOI:10.1016/S0040-4039(98)01026-0

Products guided by the article

Product name:N'-[9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-8-(dimethylamino-methyleneamino)-9H-purin-6-yl]-N,N-dimethyl-formamidine

Cas No:211676-20-9

R&D Labs maybe for 211676-20-9

Jintan City Mego Chemical Co., Ltd

Contact:+86-0519-82814387

Address:23# Dengguan Town, Jintan, Jiangsu Province, China
fujian quanzhoushi boshi environmental protecyion project co.ltd

Contact:+8615905095093

Address:208 xuefu shangcheng store,chengdong street,fengze district,quanzhou city,fujian province,China
Reliable Pharmatech (Tianjin) Co., Ltd.

Contact:86-22-28567687

Address:Zuoanmingdi, Xianshuigu, Jinnan District
Yicheng Goto Pharmaceuticals Co.,Ltd.

Contact:+86 710 3423122

Address:5th Floor,East Gate of Building #2,Servo-Industrial Park,1st Qilin Road,Xiangyang,Hubei,China
Guangxi Nanning Guangtai Agriculture Chemical Co.,Ltd

Contact:+86-771-2311266

Address:Room703,Building12, Software Park Phase II,NO.68,Keyuan Road,Nanning City,Guangxi,China

Relevant to this article

Design, synthesis, and activity of 2-imidazol-1-ylpyrimidine derived inducible nitric oxide synthase dimerization inhibitors

Doi:10.1021/jm061319i
(2007)
Functional nitroxyls for use in delayed-onset polyolefin cross-linking

Doi:10.1021/ma3016135
(2012)
Bioluminescent properties of fluorinated semi-synthetic aequorins

Doi:10.1016/S0040-4039(98)01115-0
(1998)
Competitive formation of η¹-1-phosphaallene and 1H-phosphirene complexes

Doi:10.1039/a804385j
(1998)
4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10

Doi:10.1016/j.ejmech.2018.06.047
(2018)
Exploration of modalities in building α-O-linked systems through glycal assembly: A total synthesis of the mucin-related F1α antigen

Doi:10.1021/ja980724z
(1998)

Article Doi