211696-44-5Relevant academic research and scientific papers
A PLE-based resolution of cocaine, pseudococaine, and 6-and 7-methoxylated cocaine analogues
Kozikowski,Simoni,Baraldi,Lampronti,Manfredini
, p. 441 - 444 (1996)
The enzymatic hydrolysis of racemic cocaine and cocaine analogues using pig liver esterase (PLE) is shown to afford a practical means for achieving their chemical resolution. This reaction was found to proceed not only with good enantioselectivity, but with an interesting chemoselectivity as well.
