211746-20-2

Upstream product

• 54483-54-4 (+)-2β-hydroxyethyl-3-cyclopenten-1β-ol 
• 34638-25-0 (1R,5S)-2-oxabicyclo[3.3.0]oct-6-en-3-one 
• 124-63-0 methanesulfonyl chloride 
• 211746-26-8 (1R,2S)-2-{2-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethyl}-cyclopent-3-enol 

Downstream Products

• 211746-23-5 ((1S,2S)-2-{2-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethyl}-cyclopent-3-enyl)-(6-chloro-5-nitro-pyrimidin-4-yl)-amine 
• 211746-22-4 (1S,2S)-2-{2-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethyl}-cyclopent-3-enylamine 
• 211746-21-3 (1S,2S)-2-(2-azidocyclopent-4-enyl)ethanol (4,4'-dimethoxy)triphenylmethyl ether 

Relevant academic research and scientific papers

Stereoselective synthesis of carbocyclic α-L-homonucleosides

The synthesis of several optically pure carbocyclic α-L-isomeric homonucleosides [3a-e, 6a,b, 7a,b, 10a-d] is reported. The (1R,5S)-2- oxabicyclo[3.3.0]oct-6-en-3-one 1 was used as a chiral starting material.

Synthesis of enantiomerically pure carbocyclic α-L-isomeric homonucleosides

Synthesis of hitherto unknown carbocyclic α-L-isomeric homonucleosides (8a-b, 9a-b) is described. The key intermediate 6 was synthesized from the known compound 1 as a chiral starting material. Construction of the heterocyclic moiety around the amino group of 6 afforded carbocyclic α-L- isomeric 2',3'-dideoxyhomonucleosides 8a-b and their 2',3'-didehydro-2',3'- dideoxy derivatives 9a-b.