211805-79-7

Upstream product

• 37526-88-8 benzyl tiglate 

Downstream Products

• 58801-71-1 methyl {(R)-5-[(E,E)-hexa-1,3-dienyl]-2,5-dimethyl-4-oxo-4,5-dihydrofuran-3-yl}carboxylate 
• 211805-90-2 (2S,3R)-2,3-Dimethyl-aziridine-1,2-dicarboxylic acid dibenzyl ester 
• 211805-80-0 (4R,5S)-4,5-Dimethyl-2,2-dioxo-2λ⁶-[1,3,2]dioxathiolane-4-carboxylic acid benzyl ester 
• 211805-81-1 (2S,3S)-2-Azido-3-hydroxy-2-methyl-butyric acid benzyl ester 
• 211805-84-4 (2S,3S)-2-Bromo-3-hydroxy-2-methyl-butyric acid benzyl ester 
• 211805-89-9 (2S,3R)-2,3-dimethylaziridine-2-carboxylic acid benzyl ester 
• 114179-07-6 (2S,3S)-α-methylthreonine 

Relevant academic research and scientific papers

Total syntheses of the dihydrofuranonecarboxylate natural products gregatin b and e: Gram-scale synthesis of (+)-gregatin b and unambiguous assignment of the stereostructure of (+)-gregatin e

We synthesized the dextrorotatory enantiomers of gregatin B (1.3 g scale) and E, establishing their diene side chains in the last step by Heck coupling with variable iodoolefins. Their counterpart was synthesized in 30% overall yield and with high enantio

Synthetic studies on a cyclic hexadepsipeptide GE3: Stereoselective construction of the acyl side chain segment

Stereoselective synthesis of the acyl side chain segment 2 of GE3 (1), a potent inhibitor of cell progression of the cell cycle from the G1 to S phase, has been achieved by using Sharpless' asymmetric dihydroxylation and Evans' and Paterson's stereoselective aldol methodologies.