211860-59-2Relevant academic research and scientific papers
Synthesis of terminal disaccharide elements corresponding to the Ogawa and Inaba antigenic determinant from Vibrio cholerae O1
Arencibia-Mohar, Adriana,Ariosa-Alvarez, Alina,Madrazo-Alonso, Odalys,Abreu, Elba Gonzalez,Garcia-Imia, Luis,Sierra-Gonzalez, Gustavo,Verez-Bencomo, Vicente
, p. 163 - 170 (1998)
Vibrio cholerae O1 LPS terminal mono- and disaccharide elements were synthesized by reduction of the azido group in several 4-amino-4,6-dideoxy- D-mannose mono- and disaccharide derivatives, followed by coupling with 2,4- di-O-acetyl-3-deoxy-L-glycero-tetronic acid in the presence of 2-ethoxy-l- ethoxycarbonyl-1,2-dihydroquinoline. This compound represents a useful model in order to elucidate the size of the epitopes which define Ogawa and Inaba serotypes from Vibrio cholerae O1.
