79778-86-2

Upstream product

• 59025-03-5 (S)-acetoxysuccinic anhydride 
• 100-51-6 benzyl alcohol 
• 108-24-7 acetic anhydride 
• 83477-74-1 2-R-hydroxysuccinic acid 1-benzylester 

Downstream Products

• 211860-59-2 (R)-2,4-Diacetoxy-butyric acid benzyl ester 
• 211860-58-1 (R)-2-Acetoxy-4-hydroxy-butyric acid benzyl ester 

Relevant academic research and scientific papers

METHOD FOR PREPARING COAGULATION FACTOR XIA INHIBITOR AND INTERMEDIATE THEREOF

The present disclosure involves a method for preparing a coagulation factor XIa inhibitor and an intermediate thereof. Specifically, the present disclosure involves a method for preparing an oxypyridine amide derivative. The method has the advantages of high yield, good product purity, and mild reaction conditions.

Synthesis of terminal disaccharide elements corresponding to the Ogawa and Inaba antigenic determinant from Vibrio cholerae O1

Vibrio cholerae O1 LPS terminal mono- and disaccharide elements were synthesized by reduction of the azido group in several 4-amino-4,6-dideoxy- D-mannose mono- and disaccharide derivatives, followed by coupling with 2,4- di-O-acetyl-3-deoxy-L-glycero-tetronic acid in the presence of 2-ethoxy-l- ethoxycarbonyl-1,2-dihydroquinoline. This compound represents a useful model in order to elucidate the size of the epitopes which define Ogawa and Inaba serotypes from Vibrio cholerae O1.