211869-53-3

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 492-41-1 (1R,2S)-norephedrine 
• 688-61-9 Triallylborane 
• 108591-33-9 N-((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-4-methylbenzene sulfonamide 

Downstream Products

• 4383-23-7 (S)-1-phenylbut-3-en-1-amine 
• 115224-13-0 (R)-4-amino-4-phenyl-1-butene 

Relevant academic research and scientific papers

Enantioselective synthesis of optically active homoallylamines by nucleophilic addition of chirally modified allylboranes to N-silylimines

Enantioselectivity in the allylboration of W-silylimines with a variety of chirally modified allylboron reagents has been examined. Optically active N-sulfonylarhino alcohols (16,17 and 19) derived from D-camphor and norephedrine were found to be efficient chiral ligands for the allylboration reagent. These reagents smoothly reacted with Ar-silylimines to give the corresponding homoallylic amines in a high level of enantioselectivity up to 96% ee.