211992-53-9

Basic information

• Product Name: diethyl [2-(ethoxycarbonyl)-3-phenyl-2-(E)-propenyl]malonate
• Synonyms: diethyl [2-(ethoxycarbonyl)-3-phenyl-2-(E)-propenyl]malonate
• CAS NO: 211992-53-9
• Molecular Weight: 348.396
• Mol File: 211992-53-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: diethyl [2-(ethoxycarbonyl)-3-phenyl-2-(E)-propenyl]malonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl [2-(ethoxycarbonyl)-3-phenyl-2-(E)-propenyl]malonate(211992-53-9)
• EPA Substance Registry System: diethyl [2-(ethoxycarbonyl)-3-phenyl-2-(E)-propenyl]malonate(211992-53-9)

Safety Data

• Hazardous Substances Data: 211992-53-9(Hazardous Substances Data)

Upstream product

• 105479-98-9 ethyl 2-(acetoxy(phenyl)methyl)acrylate 
• 105-53-3 diethyl malonate 

Relevant articles and documents

Novel [1,N]-Carbon to Carbon Rearrangement of an Ester Group via Organotitanium Intermediates Wherein the N Varies from 2 to 5. Full Scope and Limitation Leading Predominantly to the Rearrangement

Malonates and methanetricarboxylates having an unsaturated side chain such as 2, 12, 20, 22, 24, 31, or 37 underwent a new ester rearrangement reaction promoted by (η2-propene)Ti(O-i-Pr)2 to afford the succinate derivative 4 or α,β-unsaturated ester 17, 21, 23, 25, 34, or 38 via the migration of the ester group from its original bis- or tris-ester position to the acetylene- or olefin-litanium complex. It has been found that the side reactions competing with the desired migration are dealkylation of the side chain of the ester and a simple cyclization. The substrates and conditions which allow the ester migration a preferential path were determined as well as the scope and limitation of this reaction.