212010-22-5Relevant academic research and scientific papers
A novel β-amino acid in cytotoxic peptides from the cyanobacterium Tychonema sp.
Mehner, Christian,Mueller, Daniela,Krick, Anja,Kehraus, Stefan,Loeser, Reik,Guetschow, Michael,Maier, Armin,Fiebig, Heinz-Herbert,Brun, Reto,Koenig, Gabriele M.
, p. 1732 - 1739 (2008)
The cyclic dodecapeptides tychonamide A (1) and B (2) isolated from the methanolic extract of the cyanobacterium Tychonema sp. contain the novel β-amino acid 3-amino-2,5,7-trihydroxy-8-phenyloctanoic acid (Atpoa). Compounds 1 and 2 have cytotoxic activity
Crystallization-induced asymmetric transformations (CIAT): Stereoconvergent acid-catalyzed lactonization of substituted 2-amino-4-aryl-4-hydroxybutanoic acids
Berkes, Dusan,Kolarovic, Andrej,Manduch, Robert,Baran, Peter,Povazanec, Frantisek
, p. 1927 - 1934 (2007/10/03)
Acid-catalyzed lactonization in dilute hydrochloric acid of N-substituted 2-amino-4-aryl-4-hydroxybutanoic acids with electron donating aryl substituents is stereoconvergent. The stereochemical outcome is controlled by the precipitation of little soluble
