21203-48-5

Upstream product

• 1121-54-6 1,3-Cyclohexadiene-1-carbaldehyde 
• 14958-13-5 diethyl-buta-1,3-dienyl-amine 
• 107-02-8 acrolein 
• 100400-03-1 2-diethylamino-cyclohex-3-enecarbaldehyde 
• 4048-33-3 6-amino-1-hexanol 
• 530-62-1 1,1'-carbonyldiimidazole 
• 30810-15-2 methyl cyclohexa-1,3-diene-1-carboxylate 

Downstream Products

• 32833-06-0 cyclohexa-1,3-dien-1-ylmethyl acetate 
• 143471-24-3 1-(hydroxymethyl)-2,3-diazabicyclo<2.2.2>oct-2-ene 
• 396715-58-5 1-(aminomethyl)-2,3-diazabicyclo[2.2.2]oct-2-ene 
• 402488-35-1 toluene-4-sulfonic acid 2,3-diaza-bicyclo[2.2.2]oct-2-en-1-ylmethyl ester 
• 81427-68-1 1,3-cyclohexadienylmethyl methacrylate 
• 1313618-26-6 4-methyl-N-[(1,3-cyclohexadien-1-yl)methyl]-N-(2-propynyl)-benzenesulfonamide 
• 1313618-40-4 C₁₇H₁₉NO₂S 

Relevant academic research and scientific papers

2-(Chlorodiisopropylsilyl)-6-(trimethylsilyl)phenyl triflate: A modified platform for intramolecular benzyne cycloadditions

2-(Chlorodiisopropylsilyl)-6-(trimethylsilyl)phenyl triflate serves as an efficient aryne precursor for intramolecular benzyne [4 + 2] or (2 + 2 + 2) cycloadditions. Key features of this precursor are (1) rapid connection of various arynophiles to the pre

Decarboxylative and dehydrative coupling of dienoic acids and pentadienyl alcohols to form 1,3,6,8-tetraenes

Dienoic acids and pentadienyl alcohols are coupled in a decarboxylative and dehydrative manner at ambient temperature using Pd(0) catalysis to generate 1,3,6,8-tetraenes. Contrary to related decarboxylative coupling reactions, an anion-stabilizing group i

Exploiting long-lived molecular fluorescence

Fluorophores based on the azo chromophore 2,3-diazabicyclo[2.2.2]oct-2-ene, referred to as fluorazophores, display an exceedingly long fluorescence lifetime. Besides the use in time-resolved screening assays, where the long-lived fluorescence can be time-gated, thereby reproving the signal to background ratio, a distinct application of fluorazophores lies in the area of biopolymer dynamics. For this purpose, one chain end is labeled with a fluorazophore and the other one with an efficient fluorescence quencher. The fluorescence lifetime of the probe/quencher-labeled peptide then reflects the kinetics of intramolecular end-to-end collision. Applications to polypeptides are described and control experiments which establish the nature of the quenching mechanism as a diffusive process requiring intimate probe/quencher contact are described.

Methods for the integrated synthesis and purification of oligonucleotides

The present invention discloses novel methods for the integrated synthesis and purification of oligonucleotides. The methods employ novel capping reagents carrying two functional groups. The first functional group provides for a smooth and efficient cappi