212051-26-8

Basic information

• Product Name: 3,4-dimethoxybenzyl 2,2,3,3,4,4,4-heptafluorobutyrimidate
• Synonyms: 3,4-dimethoxybenzyl 2,2,3,3,4,4,4-heptafluorobutyrimidate
• CAS NO: 212051-26-8
• Molecular Weight: 363.232
• Mol File: 212051-26-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,4-dimethoxybenzyl 2,2,3,3,4,4,4-heptafluorobutyrimidate(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dimethoxybenzyl 2,2,3,3,4,4,4-heptafluorobutyrimidate(212051-26-8)
• EPA Substance Registry System: 3,4-dimethoxybenzyl 2,2,3,3,4,4,4-heptafluorobutyrimidate(212051-26-8)

Safety Data

• Hazardous Substances Data: 212051-26-8(Hazardous Substances Data)

Upstream product

• 375-00-8 heptafluorobutyronitrile 
• 93-03-8 (3,4-dimethoxyphenyl)methanol 
• 662-50-0 heptafluorobutyramide 

Downstream Products

• 212051-39-3 methyl 3-(3,4-dimethoxy-benzyloxy)-2-(R)-methyl-propionate 

Relevant articles and documents

Activated dimethyl sulfoxide dehydration of amide and its application to one-pot preparation of benzyl-type perfluoroimidates

Various types of primary amides were treated under an activated dimethyl sulfoxide (DMSO) species, (COCl)2-DMSO and Et3N, as a dehydrating agent to obtain nitriles in excellent yield. This dehydration system was extended to a one-pot preparation of perfluoroimidates via volatile perfluoronitriles from perfluoroamides. Fifteen benzyl-type perfluoroimidates can be prepared in 70-90% yield as more stable imidates than the trichloro analogue. MPM- and DMPM-perfluoroimidates can be used to protect alcohols in place of the trichloroacetimidate with excellent chemical properties and in comparable yields.