375-00-8

Basic information

• Product Name: HEPTAFLUOROBUTYRONITRILE
• Synonyms: Heptafluorobutyronitrile97%;Heptafluorobutanenitrile;Butanenitrile, heptafluoro-;CF3(CF2)2CN;heptafluoro-butanenitril;Perfluorobutyronitrile;HEPTAFLUOROBUTYRONITRILE;HEPTAFLUOROBUTYRONITRILE 97%
• CAS NO: 375-00-8
• Molecular Formula: C₄F₇N
• Molecular Weight: 195.04
• EINECS: 206-781-6
• Mol File: 375-00-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 2-5°C
• Flash Point: °C
• Appearance: /
• Density: 1.545 g/cm³
• Vapor Pressure: 957mmHg at 25°C
• Refractive Index: 1.271
• CAS DataBase Reference: HEPTAFLUOROBUTYRONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: HEPTAFLUOROBUTYRONITRILE(375-00-8)
• EPA Substance Registry System: HEPTAFLUOROBUTYRONITRILE(375-00-8)

Safety Data

• Hazard Codes: T
• Statements: 20/21/22-36/37/38
• Safety Statements: 36/37/39-45
• RIDADR: 3162
• HazardClass: GAS, TOXIC
• Hazardous Substances Data: 375-00-8(Hazardous Substances Data)

Usage

General Description

HEPTAFLUOROBUTYRONITRILE, also known as Perfluorobutyronitrile, is a chemical compound with the formula C4F7N. It is a colorless, odorless liquid that is highly stable and nonflammable. HEPTAFLUOROBUTYRONITRILE is used as a solvent for various chemical processes and as a refrigerant in some industrial applications. It is also used in the production of specialty polymers and as a component in electronic applications such as lithium-ion batteries and semiconductor manufacturing. Due to its strong chemical stability and low reactivity, HEPTAFLUOROBUTYRONITRILE has limited potential for environmental contamination and toxicity. However, it is important to handle and dispose of it according to proper safety and environmental guidelines.

InChI:InChI=1/C4F7N/c5-2(6,1-12)3(7,8)4(9,10)11

Upstream product

• 662-50-0 heptafluorobutyramide 
• 375-16-6 heptafluorobutyryl chloride 
• 118949-58-9 sodium (difluoroamino)difluoromethyltetrazolate 
• 460-19-5 ethanedinitrile 
• 754-34-7 1,1,1,2,2,3,3-heptafluoro-3-iodo-propane 
• 54743-47-4 C₃F₇COHNSO₂C₆H₅ 
• 12001-89-7 bis(η-isopsopylbenzene)chromium(0) 
• 812-47-5 N,N-Difluor-nonafluor-n-butylamin 
• 1001-56-5 buta-2,3-dienenitrile 

Downstream Products

• 630-18-2 tert-butyl isocyanide 
• 2252-84-8 HFC-227ca 
• 425-16-1 4,4,5,5,6,6,6-heptafluoro-2,2-dimethyl-hexan-3-one 
• 425-22-9 Propyl-heptafluorpropyl-keton 
• 559-91-1 1-phenylperfluorobutan-1-one 
• 375-02-0 2,2,3,3,4,4,4-heptafluorobutanal 
• 375-19-9 2,2,3,3,4,4,4-heptafluoro-butyramidine 
• 915-76-4 2,4,6-tris-heptafluoropropyl-[1,3,5]triazine 
• 4192-05-6 2,2,3,3,4,4,4-Heptafluor-buttersaeureimido-<2-propylester> 
• 4078-17-5 2.2.3.3.4.4.4-Heptafluorbuttersaeure-imido-phenylester 
• 662-50-0 heptafluorobutyramide 
• 13709-36-9 xenon difluoride 
• 112144-32-8 n-C₃F₇CNXeF cation 
• 4192-06-7 Propan-2-oxim-O-<2,2,3,3,4,4,4-heptafluor-imido-butyrat> 

Relevant articles and documents

Method for preparing perfluorinated nitrile through gas phase catalysis

The invention discloses a method for preparing perfluorinated nitrile through gas phase catalysis. The method comprises the following steps: a, in the absence of a catalyst, enabling acyl fluoride R1COF or perfluor substituted ethylene oxide Cyclo-CF2-CR2R3-O- to perform a gas phase amination reaction with an ammonia gas or a primary amine compound, to obtain amide of which a general formula is R1CONH2 or CR2R3FCONH2, wherein general formulas of R1, R2 and R3 are CnF[2n+1], CxF[2x+1], and CyF[2y+1], wherein x and y are non-negative integer sets, x+y=n, and n is a positive integer set; and b, in the presence of the catalyst, dehydrating the amide R1CONH2, to obtain the perfluorinated nitrile R1CN. The method is short in reaction route, and the perfluor substituted ethylene oxide or the acylfluoride is easily obtained. A total yield of the perfluorinated nitrile is high, and the route is easy for continuous industrialization.

Activated dimethyl sulfoxide dehydration of amide and its application to one-pot preparation of benzyl-type perfluoroimidates

Various types of primary amides were treated under an activated dimethyl sulfoxide (DMSO) species, (COCl)2-DMSO and Et3N, as a dehydrating agent to obtain nitriles in excellent yield. This dehydration system was extended to a one-pot preparation of perfluoroimidates via volatile perfluoronitriles from perfluoroamides. Fifteen benzyl-type perfluoroimidates can be prepared in 70-90% yield as more stable imidates than the trichloro analogue. MPM- and DMPM-perfluoroimidates can be used to protect alcohols in place of the trichloroacetimidate with excellent chemical properties and in comparable yields.

Perfluorination of Allene Derivatives by Direct Fluorination

Perfluoropropane was prepared from allene with elemental fluorine in the presence of sodium fluoride in 84percent yield for the first time.The reaction of allene with elemental fluorine afforded 2,2-difluoropropane in the absence of sodium fluoride.Methoxyallene and cyanoallene were perfluorinated with elemental fluorine in the presence of sodium fluoride to give heptafluoropropyl trifluoromethyl ether and heptafluoropropyl cyanide in good yields respectively.In addition, the direct fluorination of cyanoallene in the presence of cesium fluoride afforded N,N-difluorononafluorobutylamine in 95percent yield.