212062-49-2Relevant academic research and scientific papers
New generation dopaminergic agents. 7. Heterocyclic bioisosteres that exploit the 3-OH-phenoxyethylamine D2 template
Mewshaw, Richard E.,Nelson, James A.,Shah, Uresh S.,Shi, Xiaojie,Mazandarani, Hossein,Coupet, Joseph,Marquis, Karen,Brennan, Julie A.,Andree, Terrance H.
, p. 2593 - 2598 (2007/10/03)
The synthesis of several bioisosteric analogs based on the 3-OH-phenoxyethylamine dopamine D2 agonist template (i.e., 3) is described. The benzimidazol-2-ones and benzthioimidazol-2-ones (7-10) and 2-trifluoromethyl-benzimidazole (13) were obse
