212072-22-5Relevant academic research and scientific papers
Unusual synthesis of new glycine antagonists via sequential aldol condensation-lactonization-elimination reaction
Giacobbe, Simone A.,Baraldi, Davide,Di Fabio, Romano
, p. 1689 - 1692 (2007/10/03)
Compounds 2 and 3 were designed in order to probe the North-East region of the strichnine-insensitive glycine binding site of the NMDA receptor. The two products were obtained readily by a tandem aldol condensation- lactonization-elimination step which af
