212117-66-3

Upstream product

• 2051-96-9 benzyl (R)-Lactate 
• 212117-42-5 (S)-2-{(R)-3-[(S)-2-(tert-Butoxycarbonyl-methyl-amino)-4-methyl-pentanoyloxy]-2-oxo-azepan-1-yl}-4-methyl-pentanoic acid 
• 212117-41-4 (S)-2-{(R)-3-[(S)-2-(tert-Butoxycarbonyl-methyl-amino)-4-methyl-pentanoyloxy]-2-oxo-azepan-1-yl}-4-methyl-pentanoic acid benzyl ester 
• 212117-39-0 benzyl (2S)-2-({4-[(4R)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]butyl}amino)-4-methylpentanoate 
• 212117-40-3 benzyl (2S)-2-[(3R)-3-hydroxy-2-oxoazepanyl]-4-methylpentanoate 
• 212117-38-9 4-[(4R)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]butanal 
• 212117-37-8 (E)-4-[(4R)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-2-butenal 

Relevant academic research and scientific papers

Epsilon-lactam analogs of the anthelmintic cyclodepsipeptide PF1022A

Conformationally restricted analogs of the anthelmintic cyclodepsipeptide PF1022A 1 were prepared by fusing a seven-membered lactam ring onto the macrocycle. Following the preparation of cyclodepsipeptide (CDP) 2 by classical chemical methods, CDPs 2 and 3 were synthesized using solid phase methodology involving cyclization-cleavage from an oxime resin.