212136-31-7Relevant articles and documents
Enantioselective synthesis of β-hydroxy-α-methyl-α-methylthio esters as precursors of anti-vic-hydroxymethyl units
Shiina, Isamu,Ibuka, Ryoutarou
, p. 6303 - 6306 (2001)
A new method for the synthesis of optically active anti-vic-hydroxymethyl units that correspond to anti-aldol derivatives is developed by way of successive enantioselective aldol and diastereoselective desulfurization reactions.
Enantioselective aldol reaction of tetrasubstituted ketene silyl acetals with achiral aldehydes for the construction of asymmetric tertiary alcohols: An application for the divergent total syntheses of buergerinins F and G
Shiina, Isamu,Iizumi, Takashi,Yamai, Yu-Suke,Kawakita, Yo-Ichi,Yokoyama, Kazutoshi,Yamada, Yo-Ko
experimental part, p. 2915 - 2926 (2010/03/30)
The asymmetric aldol reaction of heteroatom-substituted ketene silyl acetals with achiral aldehydes has been developed by the promotion of tin(II) triflate coordinated with a chiral diamine to afford the corresponding aldols having chiral tertiary alcohol
Highly enantioselective synthesis of syn- and anti-propionate aldols without diastereoselection in the chiral oxazaborolidinone-promoted aldol reaction with a silyl ketene acetal derived from ethyl 2- (methylthio)propionate
Hena, Mostofa Abu,Terauchi, Saori,Kim, Chul-Sa,Horiike, Michio,Kiyooka, Syun-Ichi
, p. 1883 - 1890 (2007/10/03)
A mixture of syn- and anti-aldol products containing an α-methylthio group were obtained in good yields with high enantioselectivities in the chiral oxazaborolidinone-promoted aldol reactions of a novel silyl ketene acetal, derived from ethyl 2-(methylthio)propionate, with aldehydes. Subsequent desulfurization resulted in an effective preparation of essentially enantiopure syn- and anti-propionate aldols which were separable.
