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(+/-)-Vincamin, also known as Vincamine, is a chemical compound derived from the periwinkle plant (Vinca minor). It is a vasodilator, which means it helps to widen blood vessels, thereby improving blood flow. This property makes it useful in the treatment of conditions such as cerebral and peripheral vascular disorders, as it can help to reduce symptoms like headaches, dizziness, and tingling in the limbs. Vincamine is also believed to have anti-inflammatory and antioxidant effects, which contribute to its therapeutic benefits. It is commonly used in pharmaceutical formulations and is known for its potential to enhance cognitive function and provide neuroprotection.

2122-39-6

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2122-39-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2122-39-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,2 and 2 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2122-39:
(6*2)+(5*1)+(4*2)+(3*2)+(2*3)+(1*9)=46
46 % 10 = 6
So 2122-39-6 is a valid CAS Registry Number.

2122-39-6Upstream product

2122-39-6Downstream Products

2122-39-6Relevant academic research and scientific papers

Synthesis of 18-hydroxyvincamines and epoxy-1,14-secovincamines; A new proof for the aspidospermane-eburnane rearrangement

Nemes, Andras,Szantay Jr., Csaba,Czibula, Laszlo,Greiner, Istvan

, p. 2347 - 2362 (2007)

Chemical transformations started from tabersonine were studied. A one-pot oxidative ring-transformation with permaleic acid in methanol yielded 17,18-dehydrovincamine. Hydroboration-oxidation of the latter compound led to alkaloid 17,18-dehydrovincamone. Hydroboration-oxidation of tabersonine resulted 14β-hydroxyvincadifformine and 15β-hydroxyvincadifformine. Allowing 14β- and 15β- hydroxyvincadifformines to react with permaleic acid/methanol provided 1,14-secovincamines, serving as new evidence for the mechanism of the aspidospermane-eburnane transformation. On the other hand 18β-hydroxyvincamine was obtained from 14β-hydroxyvincadifformine by reaction with 3-chloroperbenzoic acid and successive treatment with triphenylphosphine/aqueous acetic acid.

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